中国兽医杂志2016，Vol.50Issue(6)：26-32,7.
1，4－二氧喹醛酸酯合成及抑菌活性研究
Study on the Synthesis and Bacteriostasis of 1,4 -dioxide Quinoline Aldehydes Esters
摘要
Abstract
Using benzofuroxan as raw material ,two kinds of 1,4 -dioxide quinoline aldehydes esters,1,4 -dioxide quinoline -3 - methyl -2 - phenyl formate and 1,4 -dioxide quinoline -3 - methyl -2 -cinnamylformate ,were synthesized by Beirut reaction and ester exchange reaction.The yield of 1,4 -dioxide quinoline -3 -methyl -2 -phenyl formate was 29.3% and the yield of 1,4 -dioxide quinoline -3 -methyl-2 - cinnamylformate was 18.3%.Two kinds of 1,4 -dioxide quinoline aldehyde ester have obvious antibacterial activity to Escherichia coli,Staphylococcus aureus,Penicillium sp.and Bacillus subtilis.It was proved that new compounds synthesized in experiment were target compounds by measuring the melting point and spectral analysis.关键词
苯并呋咱/酯交换反应/喹醛酸酯/抑菌活性Key words
benzofuroxan/ester exchange reaction/quinoline aldehydes esters/antibacterial activity分类
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马明真,李风梅,高宝生,宋俊芬,罗星,李华..1，4－二氧喹醛酸酯合成及抑菌活性研究[J].中国兽医杂志,2016,50(6):26-32,7.基金项目
烟台市科技发展计划项目 （）
