中国畜牧兽医2016，Vol.43Issue(7)：1694-1701,8.DOI:10.16431/j.cnki.1671-7236.2016.07.006
绒山羊次级毛囊基因表达滞后性的转录组分析
Transcriptome Survey Reveals Hysteresis in Secondary Hair Follicle for Gene Regulation in Cashmere Goat
摘要
Abstract
Hair follicle is capable of self-renew and its growth cycle is a dynamic process.In order to investigate the vary of differential expression genes in the Nei Mongol cashmere goat hair folli-cles during anagen,the mRNA expression levels of different genes in skin hair follicles were de-tected from June to October using Illumina technology.Evaluation of transcriptomes was under-taken to understand the time-course gene expression involved in both follicle types.The samples were collected from June to October.Most of differentially expressed genes appeared between July to August in primary hair follicle (PF)and between August to September in secondary hair folli-cle (SF).Seven differentially expressed genes,FAM83C,LOC102185501,FYCO1,CTTNBP2NL, C6orf132,KRTAP29-1 and CRYBG3 were identified.Their expression demonstrated similar trends at different months of cashmere growth cycle and the SF postpone for about one month. These findings indicated the hysteresis in SF gene regulation comparing with PF,and could pro-vide the useful theoretical basis for the molecular mechanism of cashmere regeneration.关键词
绒山羊/毛囊/滞后性/转录组Key words
cashmere goat/hair follicle/hysteresis/transcriptome分类
生物科学引用本文复制引用
季小阳,刘斌,白雪,王宏,付绍印,苍真伟,吴江鸿,张文广..绒山羊次级毛囊基因表达滞后性的转录组分析[J].中国畜牧兽医,2016,43(7):1694-1701,8.基金项目
国家自然科学基金(31260538、30960246) （31260538、30960246）
内蒙古重大科技支撑项目 （）
