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生地提取物对雏鸡免疫器官指数和H9疫苗免疫效果的影响

刘昭 陈立功 武现军 刘佳 郭莉

中国畜牧兽医2016,Vol.43Issue(7):1780-1784,5.
中国畜牧兽医2016,Vol.43Issue(7):1780-1784,5.DOI:10.16431/j.cnki.1671-7236.2016.07.019

生地提取物对雏鸡免疫器官指数和H9疫苗免疫效果的影响

Effect of Radix rehmanniae Extract on Immune Organ Indexes and H9 Vaccine Immune Efficacy of Chicks

刘昭 1陈立功 1武现军 1刘佳 2郭莉2

作者信息

  • 1. 河北农业大学动物医学院,保定 071001
  • 2. 保定市冀农动物药业有限公司研发部,保定 071000
  • 折叠

摘要

Abstract

This study was aimed to investigate the effect of the Radix rehmanniae extract on im-mune organs indexes and H9 vaccine immune efficacy.1 200 1-day-old healthy chicks fed with bas-al diet were chosen and randomly devided into 6 Groups on 14-day-old:GroupⅠ,Ⅱ and Ⅲ adding 2‰,3‰ 0.4‰Radix rehmanniae extract,respectively;Group Ⅳ adding 1‰ astragalus polysac-charide;Group Ⅴ immunned with H9 vaccine and fed with basal diet;Group Ⅵ was blank control group which didn’t immunned with H9 vaccine and fed basal diet.After 7 days medicine-feeding, the samples were collected at 14,21,28,35,42,49 and 56 days and the immune organs indexes and the H9 antibody levels were determined.The results showed as follows:①Compared with groupⅥ,the spleen and bursa indexes of groupⅠ,Ⅱ,Ⅲ and Ⅳ were significantly increased (P<0.05),indicating that dietary supplementation with Radixrehmanniae extract and astragalus pol-ysaccharide could improve spleen and bursa development (P<0.05).Compared with group ⅠandⅢ,the bursa and spleen indexes of group Ⅱ were significantly increased (P<0.05),while there&nbsp;was no significant difference between group Ⅱ and Ⅳ (P>0.05 ).②Dietary supplementation with Radix rehmanniae extract and astragalus polysaccharide could improve H9 antibody titers and hold it at a higher level.Compared with group Ⅰand Ⅲ,the H9 antibody titer of group Ⅱwas significantly increased from 42 days (P<0.05),while there was no significant difference be-tween group Ⅱ and Ⅳ (P>0.05).In conclusion,the Radix rehmanniae extract could improve immune organs development and immune function of chicks,and keep antibody titers at high lev-els when matches with H9 vaccine.And the recommended supplemental level of Radixrehmanni-ae extract was 2‰ in diet for chicks.

关键词

雏鸡/地黄/黄芪多糖/免疫/H9 疫苗

Key words

chicks/Radixrehmanniae/astragalus polysaccharide/immunization/H9 vaccine

分类

农业科技

引用本文复制引用

刘昭,陈立功,武现军,刘佳,郭莉..生地提取物对雏鸡免疫器官指数和H9疫苗免疫效果的影响[J].中国畜牧兽医,2016,43(7):1780-1784,5.

基金项目

河北省现代农业产业技术体系蛋鸡产业创新团队专项资金资助 ()

中国畜牧兽医

OA北大核心CSTPCD

1671-7236

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