中国药房2016，Vol.27Issue(20)：2781-2782,2783,3.DOI:10.6039/j.issn.1001-0408.2016.20.14
我院老年科患者药品不良反应发生的影响因素分析
Analysis of Influential Factors of ADR Occurred in Patients of Geriatrics Department in Our Hospital
赵红英 1杨国涛 2王海滨 1张惠芳 1王文浩 1祁景蕊1
作者信息
- 1. 沧州市中心医院老年科，河北沧州 061001
- 2. 沧州市中心医院神经内三科，河北沧州 061001
- 折叠
摘要
Abstract
OBJECTIVE:To investigate the influential factors of adverse drug reaction(ADR)in elderly patients during medi-cation,and to provide reference for reducing the incidence of ADR in geriatrics department. METHODS:The clinical data of elder-ly patients admitted to our hospital from Jan. 2011 to Dec. 2015 were collected and analyzed by single factor and unconditional Loigstic multiple regression analysis. The risk influential factors of ADR were investigated. RESULTS:A total of 1 680 patients re-ceived drug therapy,and the incidence of ADR was 7.92%(133/1 680). Organs/systems involved in ADR were mainly allergic re-action(49 cases,36.84%)and digestive system(48 cases,36.09%). The results of single factor analysis showed that the age of patients,drug dosage,route of administration,treatment course,the type numbers of drug combination and others were the inde-pendent influential factors of ADR. By unconditional Loigstic multiple regression analysis,it was found that the risk of ADR in-creased with the drug dosage,treatment course,intraverous administration and various drugs use,etc. CONCLUSIONS:It is nec-essary to pay attention to ADR monitoring,particularly risk factors monitoring of ADR in the elderly patients,strengthen medica-tion guidance to improve medication compliance,take the necessary preventive measures to reduce the incidence of ADR.关键词
老年患者/药品不良反应/影响因素Key words
Elderly patients/ADR/Influential factors分类
医药卫生引用本文复制引用
赵红英,杨国涛,王海滨,张惠芳,王文浩,祁景蕊..我院老年科患者药品不良反应发生的影响因素分析[J].中国药房,2016,27(20):2781-2782,2783,3.
