中国药物经济学2016，Vol.11Issue(7)：90-92,3.DOI:10.12010/j.issn.1673-5846.2016.07.033
西妥昔单抗联合放化疗治疗局部晚期鼻咽癌患者的临床疗效观察
Clinical Efficacy of Rituximab Combined with Chemotherapy in the Treatment of Patients with Locally Avanced Nasopharyngeal Carcinoma
孙建华 1李佳2
作者信息
- 1. 辽宁省锦州市中心医院，辽宁锦州 121000
- 2. 辽宁医学院附属第一医院，辽宁锦州 121000
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy of the combination of rituximab and chemotherapy in the treatment of localy advanced nasopharyngeal carcinoma.Methods From June 2014 to December 2015,100 patients with localy advanced nasopharyngeal carcinoma in Jinzhou Central Hospital of Liaoning province were selected as the research object.According to the random number table method,the patients were divided into observation group and control group,each of 50 cases.Patients in the observation group were treated with the combination of chemotherapy and radiotherapy.The patients in the control group were treated with conventional intensity modulated radiation therapy.The treatment effect and adverse reaction were compared between the two groups.Results Observation of patients in the treatment group total efficiency was significantly higher than that of the control group,the difference is statisticaly significant(P<0.05);after treatment observed groups of white blood cels reduce the incidence rate of control group significantly,the incidence of oral mucositis,acne like rash rate was significantly higher than that of the control group,the differences were statisticaly meter significance(P<0.05). Conclusion The clinical efficacy of rituximab combined with chemotherapy in the treatment of localy advanced nasopharyngeal carcinoma is accurate, with less adverse reaction and high clinical application value.关键词
西妥昔单抗/放化疗/局部晚期鼻咽癌Key words
West rituximab/Radiotherapy and chemotherapy/Localy advanced nasopharyngeal carcinoma分类
医药卫生引用本文复制引用
孙建华,李佳..西妥昔单抗联合放化疗治疗局部晚期鼻咽癌患者的临床疗效观察[J].中国药物经济学,2016,11(7):90-92,3.
