中华耳科学杂志2016,Vol.14Issue(2):181-185,5.DOI:10.3969/j.issn.1672-2922.2016.02.011
梅尼埃病眼肌前庭诱发肌源性电位的临床研究
Ocular vestibular evoked myogenic potentials in patients with Meniere's disease
饶任东 1孙勍 2彭新 2计莉 2张永彬 2王宁 2单希征1
作者信息
- 1. 安徽医科大学武警总医院临床学院 合肥230032
- 2. 中国武装警察部队总医院眩晕病研究所 北京100039
- 折叠
摘要
Abstract
Objectives To report ocular vestibular evoked myogenic potential (oVEMP) results in a group of patients with Meniere's disease. Methods We enrolled 66 patients with Meniere's disease as the observation group and 27 (54 ears) age-and gender-matched normal subjects as the control group. Both patients and normal subjects underwent conventional oVEMP tests in bilateral ears. The results of the affected ears were compared with the contralateral ears and with the normal controls. Results oVEMPs were elicited in 30 affected ears (41.7%), 33 contralateral ears (55.0%) and all normal ears (100.0%). Difference in response rate was not found between the affected ears and the contralateral ears (P>0.05 ), but be-tween both affected ears and contralateral ears in patients and the normal controls (P<0.05). There were differences in the amplitude and asymmetry ratio among the affected ears, contralateral ears and control ears (P<0.05), but not in the latency. Overall, in patients with Meniere's disease, the rate of successful oVEMPs induction decreased as hearing grades worsened. Conclusion The rate of oVEMP responses in patients with Meniere’s disease (in both the affected and contralateral ears, but especially in the affected ear) is significantly lower than in normal subjects, suggesting damage to utricular functions in these patients. oVEMP examination can be used to evaluate utricular functions in Meniere’s disease, and guide diagnosis and treatment.关键词
梅尼埃病/眼肌前庭诱发肌源性电位/椭圆囊/前庭Key words
Meniere's disease/ocular vestibular evoked myogenic potential/utricular function/vestibule分类
临床医学引用本文复制引用
饶任东,孙勍,彭新,计莉,张永彬,王宁,单希征..梅尼埃病眼肌前庭诱发肌源性电位的临床研究[J].中华耳科学杂志,2016,14(2):181-185,5.