中华耳科学杂志2016，Vol.14Issue(2)：304-307,4.DOI:10.3969/j.issn.1672-2922.2016.02.036
MicroRNA在中耳胆脂瘤发病机制研究进展
Research progress of MicroRNA in the pathogenesis of cholesteatoma
摘要
Abstract
MicroRNA which has variety of biological functions in cells is a small RNA molecule in the organism, par-ticipates in transcriptional regulation, energy metabolism, growth, reproduction and so on. MicroRNAs are important mole-cules in cell gene regulation in body, and exercise a variety of biological function. In recent years, a large number of molecu-lar biology researches in pathogenesis of cholesteatoma of middle ear , have made a new progress of which miRNAs study and opened a new field.MiR-21 may be related with the occurrence and development of cholesteatoma of middle ear, and has played a potential role in cholesteatoma of middle ear in growing and diffusing. This paper reviewed the researching progress of the miR-21 and cellular signaling pathways and their interaction in occurrence mechanism and development of cholesteatoma of middle ear .关键词
中耳胆脂瘤/微小RNAs/发病机制Key words
Cholesteatoma of middle ear/MicroRNAs/Pathogenesis分类
医药卫生引用本文复制引用
巴合提江·托克吉各特,阿依恒·曲库尔汗..MicroRNA在中耳胆脂瘤发病机制研究进展[J].中华耳科学杂志,2016,14(2):304-307,4.基金项目
新疆维吾尔自治区自然科学基金项目（2013211A098）Project supported by the natural science foundation of the Xinjiang Uygur Autonomous Region (2013211A098) （2013211A098）
