中华骨质疏松和骨矿盐疾病杂志2016，Vol.9Issue(2)：122-128,7.DOI:10.3969/j.issn.1674-2591.2016.02.004
50岁以上男性体质量指数、体质成分、骨密度的变化特征及其相关性分析
Relationship among aging, body composition, body mass index, and bone mass density in elderly men over 50-year-old
摘要
Abstract
Objective To investigate the aged-related changes in body composition , body mass index ( BMI) , and bone mineral density ( BMD) , and to analyze the relationship between body composition and BMD in elderly men over 50-year-old.Methods The present study was a retrospective analysis of the body composition , BMI, and BMD of 358 Chinese male outpatients over 50 years of age who were recruited from our hospital between 2009 and 2011 .Qualified subjects were stratified according to age and BMI .To compare the differences of body composition among different groups , and to analyze the impact of BMD according to the changes of body composition .Results Although there were no signifi-cant differences in BMI among the age groups , there was a significant decline in height and weight according to age ( both P=0.000 ) .The LMI ( Lean mass index ) and FFMI ( Fat free mass index ) also declined with age ( both P=0.000 ) whereas the FMI increased ( P=0.015 ) .Although the absolute values of BMC and LM declined with age ( P=0.003 and P=0.000 , respectively ) , there was no significant difference in FM .There was an increase in %FM ( P=0.000 ) and a decrease in %LM (P=0.000) with age.The femoral neck (FN) and total hip (TH) BMD significantly declined with age ( P=0.000 and P=0.003 , respectively ) .BMD increased at all sites ( all P<0.01 ) as BMI increased but there were declines in the detection rates of osteoporosis and osteopenia ( both P=0.000 ) .Logistic regression revealed that a decline in BMI was an independent risk factor of osteoporosis or osteopenia , while an increase in BMI was a protective factor for BMD.At the same time, BMD in L1-4 exhibited a significant positive correlation with FMI (P=0.000) and the femoral neck and total hip BMDs had significant positive correlation with FFMI and LMI , respectively ( both P=0.000 ) .Conclusion These data indicated that in elderly males older than 50 years, an increased BMI was protective for BMD while FMI were protective for BMD in L1-4 , LMI and FFMI were protective for BMD in the femoral neck and total hip.关键词
老年男性/体质成分/体质量指数/骨密度Key words
elderly male/body composition/body mass index/bone mineral density分类
医药卫生引用本文复制引用
江颖,裴育,苗新宇,金萌萌,谷昭艳,李剑,李春霖,田慧..50岁以上男性体质量指数、体质成分、骨密度的变化特征及其相关性分析[J].中华骨质疏松和骨矿盐疾病杂志,2016,9(2):122-128,7.基金项目
国家自然科学基金青年科学基金（81300717）；解放军总医院临床科研扶持基金 （）
