中华骨质疏松和骨矿盐疾病杂志2016，Vol.9Issue(2)：143-148,6.DOI:10.3969/j.issn.1674-2591.2016.02.007
跟骨定量超声联合亚洲人骨质疏松自我评价工具在筛查社区绝经后妇女骨质疏松症中的应用
Combined use of calcaneal quantitative ultrasound with Asian osteoporosis self assessment tools in screening osteoporosis among postmenopausal women
摘要
Abstract
Objective To explore the effectiveness of combining calcaneal quantitative ultrasound ( QUS) with Asian osteoporosis self assessment tools ( OSTA ) in screening osteoporosis among postmenopausal women . Methods From Sep.2014 to Dec.2014, bone mineral density (BMD) of 118 postmenopausal women was measured in Guangzhou communities by QUS and relative information such as their ages and BMI were required through questionnaire .BMD was measured by dual-energy x-ray absorptiometry (DXA).By drawing receiver operating characteristic curve (ROC), this research evaluated the feasibility of joined use of QUS and OSTA score in osteoporosis screening , and determined the ap-propriate cut-off point .Results When OSTA and QUS were combined for screening , the regression curve was fitted as Y=-1.688 ×QUS-0.186 ×OSTA-3.973.Meanwhile, the area under the ROC (AUC) drawn by predicted value and DXA screening result was 0.847 , SE=0.041 , P=0.000 .AUC=0.847 , SE=0.041 , P=0.000 .When QUS-T and OSTA were used parallelly , the cut-off point set by OSTA≤-3 and QUS-T≤-2.2 could achieve the following fig-ures:Youden index as 0.63 , while sensitivity was 89% and specificity was 74%.Conclusion QUS and OSTA score were simple and economic methods of predicting the incidence of osteoporosis among the elderly .Setting the appropriate QUS and OSTA threshold could approch a good accuracy .It was worth in screening of osteoporosis .关键词
骨质疏松症/定量超声/亚洲人骨质疏松症自评工具/骨密度检测Key words
osteoporosis/quantitative ultrasound/Asian osteoporosis self-assessment tool/bone mineral den-sity test分类
医药卫生引用本文复制引用
张彦,刘和菊,李春海,陈庆瑜,张弛,傅光涛,丁悦..跟骨定量超声联合亚洲人骨质疏松自我评价工具在筛查社区绝经后妇女骨质疏松症中的应用[J].中华骨质疏松和骨矿盐疾病杂志,2016,9(2):143-148,6.基金项目
广东省公益研究及能力建设专项重大项目 （）
