摘要
Abstract
Objective:To observe and compare the clinical effects of Esomeprazole and Omeprazole in the treatment of reflux esophagitis.Method:One hundred cases of reflux esophagitis admitted to our hospital from May 2014 to May 2015 were selected and randomly divided into two groups,50 cases in each group.Both the two groups were treated with Mosapride,while the control group was combined with Omeprazole,the observation group was combined with Esomeprazole treatment.The symptom score,effective rate of treatment,24 h esophagus reflux times and pH value of the two groups were observed after treated for 4,8 weeks. Result:After 4,8 weeks,the total effective rate was 74.0%and 96.0%in the observation group,significantly higher than 52.0%and 70.0%of the control group, the differences were statistically significant(P<0.05).The symptom score of observation group improved better than the control group,and the 24 h esophagus reflux times,the duration ratio of esophageal pH<4 in the observation group were lower,the differences were statistically significant(P<0.05).Conclusion:Esomeprazole has more superior anti acid ability than that of Omeprazole,it can effectively improve the esophageal pH environment,shorten the esophageal mucosa by acid erosion time,which is beneficial to the alleviation of clinical symptoms and promote the healing of esophageal mucosa,it is worth popularizing and applying.关键词
反流性食管炎/抑酸治疗/埃索美拉唑/奥美拉唑Key words
Reflux esophagitis/Acid treatment/Esomeprazole/Omeprazole分类
医药卫生
