安徽农业科学2016，Vol.44Issue(19)：8-9,2.
雪白弯颈霉产环孢菌素发酵条件的优化
Optimization of Fermentation Conditions for Production of Cyclosporin from Tolypocladium inflatum
摘要
Abstract
Objective] To discuss the optimum fermentation conditions for the production of cyclosporin from Tolypocladium inflatum.[ Meth-od] Through an orthogonal experiment, the effects of culture time, culture medium, bottling capacity, and inoculation amount ( in slice) of T.inflatum on the production of cyclosporin were analyzed.[ Result] The optimum fermentation conditions for the production of cyclosporin from T.inflatum were shown as follows:the culture time was 4 d;the fermentation culture medium was composed of potato 200.00 g, manni-tol 40.00 g, and peptone 6.00 g;bottling capacity was 100 mL;inoculation amount was 9 slices.[ Conclusion] The study can provide theo-retical foundation for the improvement of yield of cyclosporin produced from T.inflatum.关键词
雪白弯颈霉/环孢菌素/正交试验/发酵条件Key words
Tolypocladium inflatum/Cyclosporin/Orthogonal experiment/Fermentation conditions分类
医药卫生引用本文复制引用
周方元,苏丹,吕国忠,姜娃,李琳琳..雪白弯颈霉产环孢菌素发酵条件的优化[J].安徽农业科学,2016,44(19):8-9,2.基金项目
大连民族大学人才引进科研项目启动基金项目（0701－110048）；中央高校自主科研基金项目（DC201502070402）；大学生创新创业训练项目（XA201612317，XA201612315）。 （）
