电子学报2016,Vol.44Issue(7):1689-1693,5.DOI:10.3969/j.issn.0372-2112.2016.07.024
一种扩展的Post类函数及其对基因调控机制的影响
The Study of an Extended Post CIass Functions and its InfIuence on the Gene Regu Iatory Mechanis m
摘要
Abstract
Theoretical analysis reveals that ordered functions play an important role in the running and dynamical be-havior of networks.Post function class has been known as the maximal ordered function.However,it only describes the posi-tive regulatory mechanism appeared in genetic regulatory networks.In this paper,we extend the Post function class so that it contains both the positive and negative regulatory mechanism.Simulation results show that the extended Post function class can present similar dynamical characters as the original Post class and Canalizing function class.It has the ability to keep or-dered behaviors and can emerge the long-range correlated dynamics.From the point of view of natural evolution,we con-clude that such abundant ordered functions are more possible to be selected as the interactions among genes.Finally,the dis-tribution of function classes on eight real systems also partially supports our conclusion.关键词
布尔网络/动态行为/Post类函数/基因调控网络Key words
Boolean network/dynamic behavior/post class function/gene regulatory network分类
信息技术与安全科学引用本文复制引用
许鹏,欧阳宏嘉,沈良忠,刘文斌..一种扩展的Post类函数及其对基因调控机制的影响[J].电子学报,2016,44(7):1689-1693,5.基金项目
国家自然科学基金(No.61272018,No.61572367,No.61174162);浙江省自然科学基金 ()