国际医药卫生导报2016，Vol.22Issue(15)：2333-2336,2338,5.DOI:10.3760/cma.j.issn.1007-1245.2016.15.041
脑梗死患者磁共振弥散加权成像ADC值演变的临床研究
A clinical study of the development of apparent diffusion coefficient on diffusion weighted MRI in patients with cerebral infarction
钟水生 1曾昭龙 1杨慧 1唐晓梅 1潘梦秋 1李志刚 1包泽岩 1胡运新 1廖华印1
作者信息
- 1. 510510 广州,广东三九脑科医院神经内科
- 折叠
摘要
Abstract
Objective To observe the changes of apparent diffusion coefficient (ADC) value on diffusion weighted imaging (DWI) after cerebral infarction,in order to identify the variation between ADC values and corresponding cerebral edema in different periods of cerebral infarction.Methods Retrospective study (2013.1-2014.8) including 269 patients at hyperacute (≤ 6 h),acute (6-24 h),necrosis (24-48 h),softening (48 h-3 w) stages of cerebral infarction were imaged with DWI.The average ADC value of the infracted lesion and contralateral normal brain were calculated respectively.And analyzed the difference of the ADC values between anterior circulation and posterior circulation,gray and white matter.Results All infracted lesions in hyperacute,acute,necrosis and softening stages showed hyperintense signal on DWI,while ADC value reduced at stroke onset.The average ADC value of hyperacute,acute,necrosis and softening stages were (0.524±0.080),(0.401±0.081),(0.369±0.084),(0.524±0.100),which showed that the curve of ADC value in cerebral infarction was similar to U-shaped.The ADC value in grey matter was higher than that in white matter [(0.455±0.126) vs.(0.432±0.103),P＜0.05],the average ADC value of anterior circulation infarction was lower than that of posterior circulation infarction [(0.431 ±0.117) vs.(0.479±0.095),P＜0.01].Conclusion ADC value can be used to estimate the type of cerebral edema,which is helpful to guide clinical treatment.关键词
脑梗死/磁共振/DWI/表观弥散系数Key words
Cerebral infarction/MR/DWI/Apparent diffusion coefficient引用本文复制引用
钟水生,曾昭龙,杨慧,唐晓梅,潘梦秋,李志刚,包泽岩,胡运新,廖华印..脑梗死患者磁共振弥散加权成像ADC值演变的临床研究[J].国际医药卫生导报,2016,22(15):2333-2336,2338,5.
