国际医药卫生导报2016，Vol.22Issue(16)：2494-2496,3.DOI:10.3760/cma.j.issn.1007-1245.2016.16.028
舒利迭治疗中-重度稳定期老年慢性阻塞性肺疾病的最佳剂量
Optimal dose of seretide in treatment of elderly patients with chronic obstructive pulmonary disease (COPD)in moderate to severe stable period
郭丽娟 1颜明布 1隋晓俊 1时新杰 1于军方 1吴京波1
作者信息
摘要
Abstract
Objective To explore the optimal dose of seretide for senile chronic obstructive pulmonary disease (COPD) in moderate to severe stable period.Methods 132 patients with moderate to severe stable COPD treated at our hospital from May,2013 to May,2015 were selected and divided into a control group (conventional therapy),a small dose group (seretide 50/250 μg),and a large dose group (seretide 50/500 μg) according to different treatment methods,44 cases for each group.The clinical efficacies were compared between these 3 groups.Results The FEV1,FEV1/FVC,FEV1％,6-MWD,and clinical symptom score were significantly better after than before the treatment in all the three groups (P＜0.05) and were best in the large dose group after the treatment,with statistical differences between these three groups (P＜0.05).After the treatment,PaO2 significantly increased and PaCO2 significantly decreased in the small dose group and the large dose group (P＜0.05) and the changes of PaO2 and PaCO2 were significantly higher in the large dose group than in the small dose group (P＜0.05).Conclusion Seretide can significantly improve pulmonary function,clinical symptoms,and so on of the elderly moderate to severe stable COPD patients and large dose has more advantages.关键词
老年慢性阻塞性肺疾病/中-重度稳定期/舒利迭/最佳剂量/疗效Key words
Elderly chronic obstructive pulmonary disease/Moderate to severe stable period/Seretide/Optimal dose/Treatment effect引用本文复制引用
郭丽娟,颜明布,隋晓俊,时新杰,于军方,吴京波..舒利迭治疗中-重度稳定期老年慢性阻塞性肺疾病的最佳剂量[J].国际医药卫生导报,2016,22(16):2494-2496,3.
