实用医学杂志2016，Vol.32Issue(15)：2462-2464,3.DOI:10.3969/j.issn.1006-5725.2016.15.012
广西地区鼻咽癌miR-451a表达与预后的关系
Expressions and significances of prognosis by MiR-451a in nasopharyngeal carcinoma in Guangxi
摘要
Abstract
Objective To investigate the expression level and the significances of prognosis by miR-451a in nasopharyngeal carcinoma (NPC) in Guangxi. Methods The expressions of miR-451a in 89 cases of nasopharyngeal carcinoma were detected by real time RT-PCR. The relation among the expression level , the clinicopathologic features of NPC and its prognosis were analyzed. Results The expression of miR-451a were found in all of nasopharyngeal carcinoma. The expression level of miR-451a in nasopharyngeal carcinoma was negative correlated to overall survival and disease free survival (P = 0.01,P = 0.04). Conclusions miR-451a may play a key role in detection of nasopharyngeal carcinoma with poor prognosis.关键词
鼻咽肿瘤/MiR-451a/荧光定量RT-PCR/预后Key words
Nasopharyngeal carcinoma/MiR-451a/Real time RT-PCR/Prognosis引用本文复制引用
莫祥兰,殷舞,韦海明,兰桂平,司勇峰,周敏燕..广西地区鼻咽癌miR-451a表达与预后的关系[J].实用医学杂志,2016,32(15):2462-2464,3.基金项目
广西壮族自治区卫生厅科研课题（编号Z2010237， Z2013355）；国家自然科学基金项目 （）
