实用医学杂志2016，Vol.32Issue(15)：2488-2490,3.DOI:10.3969/j.issn.1006-5725.2016.15.021
尘螨特异性IgE阳性儿童支气管哮喘脱敏治疗临床研究
A clinic study on desensitization treatment of bronchial asthma with positive specific IgE to dust mite in children
摘要
Abstract
Objective To investigate the efficacy and the course of desensitization treatment in bronchial asthma with positive specific IgE to dust mite in children. Methods A total of 105 children with bronchial asthma with positive specific IgE to dermatophagoides farinae allergens were randomized into the observation group and the control group. Children in the control group were treated to continue anti-asthma according to the routine of prevention and treatment children with asthma. Chinldren in the observation group were treated by dermatophagoides farinae drops in addition to the treatment of children in the control group. The recurrence of asthma was compared between two groups at 25 weeks post-treatment. At 25 weeks post-treatment , children in the observation group was randomly divided into the observation groupⅠand group Ⅱ. Children in the observation groupⅠreceived continuous treatment except for desensitization treatment. Children in the observation group II received the sublingual immunotherapy with dermatophagoides farinae drops (No.4) for 1 year in addition to the treatment in the observation groupⅠ. The recurrence of asthma was also compared between the two sub-groups. Results The rate and times of recurrence of asthma were lower in the observation group than those in the control group(P < 0.05), with no significant differences between the observation groupⅠand groupⅡ (P > 0.05). Conclusion The recurrent rate and frequency of asthma could be reduced by the sublingual immunotherapy with dermatophagoides farinae drops in children with asthma of positive specific IgE to dust mite. The course of treatment may be half year long.关键词
支气管哮喘/脱敏治疗/疗效/疗程/儿童Key words
Bronchial asthma/Desensitization treatment/Curative effect/Course of treatment/Children引用本文复制引用
蔡幸生,朱勇斌,林丽爱,黄育涛,陈素华,王金燕,林彤彤..尘螨特异性IgE阳性儿童支气管哮喘脱敏治疗临床研究[J].实用医学杂志,2016,32(15):2488-2490,3.基金项目
广东省揭阳市卫生局医学科研项目 （）
