实用医学杂志2016，Vol.32Issue(15)：2494-2497,4.DOI:10.3969/j.issn.1006-5725.2016.15.023
宫颈上皮内瘤变Ⅱ／Ⅲ级及宫颈癌中人乳头瘤病毒基因型分布的比较
Human papillomavirus genotype in cervical intraepithelial neoplasia grade Ⅱ/Ⅲ and cervical carcinoma:a comparative study
摘要
Abstract
Objective To explore the distributions of genotypes of HPV infection in CIN and cervical carcinoma. Methods Cervical exfoliated cells were collected from 365 patients with abnormal cervical histology , and subjected to genotyping assay. Results The most prevalent HPV types were 16, 18,52, 58 and 33. The prevalence ratio of HPV 33,52,58 was signi cantly lower in squamous cell carcinoma. Multiple infections decreased from CIN II/III to cervical cancer. Conclusion Besides HPV 16/18, the 52/58/33 subtypes are also important in the development of cervical cancer.关键词
宫颈上皮内瘤变/宫颈肿瘤/人乳头瘤病毒/基因分型Key words
Cervical Intraepithelial Neoplasia/Cervical Carcinoma/Human Papillomavirus/Genotyping assay引用本文复制引用
李晓琳,万晓洁,郑飞云,朱雪洁,余剑琴..宫颈上皮内瘤变Ⅱ／Ⅲ级及宫颈癌中人乳头瘤病毒基因型分布的比较[J].实用医学杂志,2016,32(15):2494-2497,4.基金项目
浙江省卫生厅医药卫生科技计划项目 （）
