实用医学杂志2016，Vol.32Issue(16)：2734-2736,3.DOI:10.3969/j.issn.1006-5725.2016.16.041
奥卡西平联合左乙拉西坦治疗小儿癫痫的疗效及安全性
Efficacy and Safety of Oxcarbazepine combined with Levetiracetam on Children with epilepsy
李志斌 1江慧敏 1肖华1
作者信息
- 1. 510160 广州市妇女儿童医疗中心神经康复科
- 折叠
摘要
Abstract
Objective To investigate the efficacy and safety of oxcarbazepine combined with levetirac-etam on children with epilepsy. Methods According to different treatments, 62 cases of children with epilepsy were divided into the OXC group (treated with oxcarbazepine, 40 cases) and the OXC combined with LEV group (treated with oxcarbazepine and levetiracetam, 20 cases). Then the therapeutic efficacy, EEG changes and ad-verse reactions of patients in the two groups were studied. Results The total efficacy was 87.5% in the OXC group, and was 95.5% of the OXC combined with LEV group, with no significant difference. EEG improvement rate was 52.5% in the OXC group and 81.8% in the OXC combined with LEV group , with significant difference (P < 0.05). The rate of adverse reactions in the OXC combined with LEV group was lower than that in the OXC group (P < 0.05). Conclusion Both levetiracetam and oxcarbazepine has good curative effect on children with epilepsy , but combination with levetiracetam can significantly decrease the epileptic discharges on EEG , with higher security.关键词
奥卡西平/左乙拉西坦/儿童癫痫Key words
Oxcarbazepine/Levetiracetam/Epilepsy引用本文复制引用
李志斌,江慧敏,肖华..奥卡西平联合左乙拉西坦治疗小儿癫痫的疗效及安全性[J].实用医学杂志,2016,32(16):2734-2736,3.
