中国感染控制杂志2016，Vol.15Issue(8)：608-611,4.DOI:10.3969/j.issn.1671-9638.2016.08.017
重症监护病房医务人员鼻前庭细菌定植情况及耐药性调查
Colonization and antimicrobial resistance of pathogens in nasal vestibular of health care workers in intensive care unit
南玲 1刘丁 1李茂圆 1方清永 1王豪 1陈萍 1黄庆宁 1成瑶1
作者信息
- 1. 第三军医大学第三附属医院野战外科研究所，重庆 400042
- 折叠
摘要
Abstract
Objective To understand colonization of pathogens in nasal vestibular of health care workers (HCWs) in intensive care unit (ICU),and provide evidence for strengthening the prevention and control of healthcare-associated infection (HAI)in ICU.Methods On may 2015,colonization status of pathogens in nasal vestibular of uninfected HCWs in ICU were actively screened,bacterial culture,isolation and identification were performed.The surveyed results were analyzed and compared with antimicrobial resistance of pathogens from patients at the same stage.Results A total of 96 HCWs were surveyed,43 pathogenic strains were isolated from different HCWs’na-sal vestibular,isolation rate and carriage rate were both 44.79%.The main pathogenic bacteria was Staphylococcus aureus(n=15,34.88%),followed by Enterobacter aerogenes (n =9,20.93%)and Klebsiella pneumoniae (K . pneumoniae ,n=7,16.28%).There was a high detection rate of pathogens from nasal vestibular of doctors,HCWs who smoked frequently and those who never exercised (all P <0.05).There were 1 strain of imipenem-resistant K . pneumoniae among 43 pathogenic strains.Resistance rate of 7 K .pneumoniae from HCWs to ampicillin/sulbactam, cefazolin,and furantoin were all >50.00%,resistance rates to cefotaxime and imipenem were 28.57% and 14.29%respectively;resistance rates of 11 strains of K .pneumoniae from patients to furantoin was 100.00% during the same stage,but were sensitive to other commonly used antimicrobial agents.Resistance rate of 4 strains of Esche-richia coli (E.coli)to ampicillin was 75.00%,to gentamicin,tobramycin,levofloxacin,ciprofloxacin,and com-pound sulfamethoxazole were all 50.00%,6 strains of E.coli isolated from patients during the same period were found to be resistant to most commonly used antimicrobial agents.Conclusion Colonization rate of pathogens is high in nasal vestibular of HCWs in ICU,active screening and monitoring on colonization of pathogens in HCWs’ nasal vestibular is significant for preventing the occurrence and cross transmission of HAI among HCWs and pa-tients.关键词
重症监护病房/医务人员/主动筛查/病原菌/耐药性/抗药性,微生物Key words
intensive care unit/health care worker/active screening/pathogenic bacteria/drug resistance/drug resistance,microbial分类
医药卫生引用本文复制引用
南玲,刘丁,李茂圆,方清永,王豪,陈萍,黄庆宁,成瑶..重症监护病房医务人员鼻前庭细菌定植情况及耐药性调查[J].中国感染控制杂志,2016,15(8):608-611,4.
