中国社区医师2016，Vol.32Issue(24)：10-11,2.DOI:10.3969/j.issn.1007-614x.2016.24.2
“补肾健脾”针刺法对绝经后骨质疏松症模型血清碱性磷酸酶水平的影响
Effect of acupuncture method of"invigorating the kidney and strengthening the spleen"on the level of serum alkaline phosphatase in postmenopausal osteoporosis model
摘要
Abstract
Objective:To observe the effect of acupuncture method of"invigorating the kidney and strengthening the spleen"on the content of alkaline phosphatase (ALP) in serum of ovariectomized rats.Methods:32 female rats were divided into the sham operation group,the model group,the acupuncture group and the estrogen group.The sham operation group did not remove the ovaries,while bilateral ovaries were removed in the other 3 groups,to made postmenopausal osteoporosis model.The sham operation group and model group were administered with equivalent saline at the same time.The acupuncture group was treated by acupuncture at bilateral Zusanli and Shenyu, Piyu points,Dazhu caveand Mingmen and Guanyuan point,and the estrogen group was treated with intragastric administration of diethylstilbestrol solution.Femoral artery blood was taken after 3 months,and the content of ALP in serum was measured.Results:The serum alkaline phosphatase levels in the model group were higher than those in the sham operation group(P<0.05).Compared with the model group,the serum ALP levels in the acupuncture group and the estrogen group were lower than those in the model group(P<0.01).Conclusion:The content of alkaline phosphatase in serum of ovariectomized rats was increased,format a high conversion osteoporosis model,after estrogen replacement and acupuncture treatment,the content of serum ALP decreased,both of the two treatments can resist the high conversion of bone metabolism,to provide part of the clinical effect of acupuncture method of"invigorating the kidney and strengthening the spleen"in the treatment of postmenopausal osteoporosis.关键词
绝经后骨质疏松症/“补肾健脾”针刺法/血清碱性磷酸酶Key words
Postmenopausal osteoporosis/Acupuncture method of"invigorating the kidney and strengthening the spleen"/Serum alkaline phosphatase引用本文复制引用
李灿,黎喜平,陈久毅,沈骏,秧荣昆,王建..“补肾健脾”针刺法对绝经后骨质疏松症模型血清碱性磷酸酶水平的影响[J].中国社区医师,2016,32(24):10-11,2.基金项目
贵州省原卫生厅课题(gzwkj2008-2-001)；贵州科技厅科技基金项目(黔科合J字[2008]2288)；贵州省教育厅自科项目[黔教科(2007)037]Fund project Subject of Health Department of Guizhou Province(gzwkj2008-2-001) （gzwkj2008-2-001）
Science and Technology Fund Project of Guizhou Science and Technology Department(Qian Kehe J word[2008]2288) （Qian Kehe J word[2008]2288）
Natural Science Project of Office of Science Education in Guizhou Province[Qian Jiaoke(2007)037]。 （2007）
