摘要
Abstract
Objective:To explore the detection value of serum homocysteine in diabetic nephropathy. Method:Eighty patients with type 2 diabetes mellitus admitted in our hospital from August 2014 to October 2015 were selected,they were divided into group A(19 patients with pure diabetes),group B(25 patients with early diabetic nephropathy),group C(20 patients with clinical diabetic nephropathy)and group D(16 patients with renal failure),35 cases with physical examinations were selected as the control group over the same period,3 mL of fasting venous bloods of patients were extracted respectively,and the serum level of homocysteine was detected by circle enzyme after centrifugationt.Result:The comparisons in fasting blood sugar and cholesterol of patients in group A,group B,group C and group D were not significantly different(P>0.05).The comparisons in excretion rates of fasting blood glucose,cholesterol and urinary albumin of patients in group A,group B,group C and group D,compared with the control group,there was statistical significance(P<0.05).The excretion rates of urine albumin and levels of serum homocysteine of patients in group A,group B,group C and group D showed the tendency of progressive,and inter-group comparison differences were significant(P<0.05).Conclusions:Serum homocysteiney delivers great detection value in diabetic nephropath,and its level can reflect the renal damage of patients with diabetic nephropathy,serum homocysteiney as an independent risk factor for diabetic nephropathy, can serve as a detection indicator to judge the occurrence and development of type 2 diabetes.关键词
2型糖尿病/血清同型半胱氨酸/糖尿病肾病Key words
Type 2 diabetes/Serum homocysteine/Diabetic nephropathy
