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胃肠癌贫血患者EPO、EPO-R和MVD的相关性研究

乔姝 孙海凤 白强 马俊兵 李雪飞 解彩霞

中国医学创新2016,Vol.13Issue(23):9-12,4.
中国医学创新2016,Vol.13Issue(23):9-12,4.DOI:10.3969/j.issn.1674-4985.2016.23.003

胃肠癌贫血患者EPO、EPO-R和MVD的相关性研究

Correlation Study between ERO,EPO-R and MVD on Patients with Gastrointestinal Cancer Anemia

乔姝 1孙海凤 1白强 1马俊兵 1李雪飞 1解彩霞1

作者信息

  • 1. 包头医学院第一附属医院 内蒙古 包头 014010
  • 折叠

摘要

Abstract

Objective:To discuss the relationship between EPO,EPO-R and microvascular density (MVD) expression on patients with gastrointestinal cancer anemia.Method:Used conventional methods to detect Hb and serum EPO concentration,EPO,EPO-R and MVD was detected by immunohischemical method for 177 patients with gastrointestinal cancer.Finally correlation analysis was carried on.Result:(1)EPO levels of 57 patients with anemia was obviously higher than that of Hb in without-anemia(P<0.05).There was obvious negative correlation between serum EPO level and Hb values(P<0.001).(2)MVD of EPO and EPO-R express positive patients was obviously higher than that of negative patients(P<0.05). There was obvious positive correlation between EPO and EPO-R and MVD(P<0.001).Conclusion:The Epo levels were increased significantly on patients with gastrointestinal cancer anemia and it’s relationship with Hb are significantly negative correlation. The expression of EPO,EPO-R and MVD were positively correlated.

关键词

胃肠癌/贫血/血红蛋白/促红细胞生成素/促红细胞生成素受体/微血管密度

Key words

Gastrointestinal cancer/Anemia/Hemoglobin/Erythropoietin/Erythropoietin receptor/Microvascular density

引用本文复制引用

乔姝,孙海凤,白强,马俊兵,李雪飞,解彩霞..胃肠癌贫血患者EPO、EPO-R和MVD的相关性研究[J].中国医学创新,2016,13(23):9-12,4.

基金项目

内蒙古包头社会发展科技支撑项目 ()

中国医学创新

1674-4985

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