中国医学创新2016，Vol.13Issue(23)：137-140,4.DOI:10.3969/j.issn.1674-4985.2016.23.039
自噬及其在肿瘤发生发展中作用的研究进展
The Research Advance of Autophagy and Its Role in Tumorigenesis
摘要
Abstract
Autophagy is a lysosomal degradation pathway that cyclic uses the damaged organelles and the macromolecular protein to maintain catabolic process of cellular homeostasis.This process has extremely close relationship with a variety of diseases including tumor. The recent research indicated that autophagy may play both positive and negative influence in different development stage of the tumor.Moreover,in different type of tumor, autophagy has different role.Therefore,the specific mechanism of autophagy in the development of tumor is becoming a research hotspot,which also has certain guiding significance for promoting the clinical treatment on tumor.Here we have a review summarized the research advance of autophagy and its role in tumor development.关键词
自噬/肿瘤/调控机制/信号通路Key words
Autophagy/Tumor/Regulatory mechanism/Signaling pathway引用本文复制引用
魏艳杰,田炜..自噬及其在肿瘤发生发展中作用的研究进展[J].中国医学创新,2016,13(23):137-140,4.基金项目
河北省自然科学基金（H2012401036）；华北理工大学大学生创新项目 （）
