中国卒中杂志2016，Vol.11Issue(7)：563-569,7.DOI:10.3969/j.issn.1673-5765.2016.07.008
中国高颅压患者视神经鞘直径的诊断价值
Optimal Optic Nerve Sheath Diameter Threshold for the Identification of Elevated Opening Pressure on Lumbar Puncture in a Chinese Population
王丽娟 1冯良枢 1姚燕 2王玉芝 1陈盈 1冯加纯 1邢英琦1
作者信息
- 1. 130021 长春吉林大学第一医院神经内科和神经科学中心
- 2. 吉林大学公共卫生学院流行病与卫生统计学教研室
- 折叠
摘要
Abstract
Ultrasonography of the optic nerve sheath diameter (ONSD) is a non-invasive and rapid method that might be helpful in the identification of increased intracranial pressure (ICP). The use of an ONSD greater than 5 mm on ultrasound as an indicator of increased ICP in a Caucasian population has been studied. However, the cut-off point of this predictor in Chinese patients has not been established. Thus, we conducted this study to identify the ONSD criterion for the detection of elevated opening pressure on lumbar puncture (LP) in a Chinese population and to investigate the inlfuencing factors. This study was a blind cross-sectional study. Patients who presented with suspected increased ICP were included. The opening pressure on LP of each participant was conifrmed. We analyzed the clinical differences between the groups of patients with abnormal and normal opening pressures on LP. A receiver operating characteristic curve was constructed to determine the ONSD cut-off point for the identiifcation of abnormal opening pressure on LP. In total, 279 patients were recruited, and 101 patients presented with elevated opening pressure on LP. ONSD was a significant independent predictor of elevated opening pressure on LP (P<0.001). However, no statistical signiifcance was observed regarding the factors that might have affected this relationship including gender, age, body mass index, waistline, head circumference, hypertension and pathological subtype. The ONSD cut-off point for the identiifcation of elevated opening pressure on LP was 4.1 mm; this cut-off yielded a sensitivity of 95% and a speciifcity of 92%. ONSD is a strong and accurate predictor of elevated opening pressure on LP. The cut-off point of this predictor in a Chinese population was remarkably lower than that found in a Caucasian population. Thus, ethnic differences should be noted when using the ONSD as an indicator of increased ICP.关键词
高颅压/视神经鞘/超声/无创Key words
Elevated intracranial pressure/Optic nerve sheath/Ultrasonography/Noninvasive引用本文复制引用
王丽娟,冯良枢,姚燕,王玉芝,陈盈,冯加纯,邢英琦..中国高颅压患者视神经鞘直径的诊断价值[J].中国卒中杂志,2016,11(7):563-569,7.
