中国卒中杂志2016,Vol.11Issue(8):704-708,5.DOI:10.3969/j.issn.1673-5765.2016.08.018
脑梗死后VEGF及bFGF对神经干细胞增殖分化的机制研究进展
New Progress in the Study of the Mechanism of bFGF and VEGF on Proliferation and Differentiation of Neural Stem Cells after Cerebral Infarction
摘要
Abstract
Because the pathogenesis of ischemic stroke is complex, so far, there are still no effective treatments. With deeper study, neural stem cells (NSCs) is taken as a new target that provides a new broad prospect for stroke. To this day, there are studies ifnding that proliferation and differentiation of NSCs was mediated by many environmental factors after cerebral arterial thrombosis, among which, vascular endothelial growth factor (bFGF) and VEGF plays important roles in the proliferation and differentiation. It provides a theoretical therapy of clinical cerebral ischemia via studying the mechanism of bFGF and vascular endothelial growth factor (VEGF) on the proliferation and differentiation of NSCs after cerebral infarction.关键词
缺血性卒中/神经干细胞/增殖/分化/碱性成纤维细胞生长因子/血管内皮生长因子Key words
Ischemic stroke/Neural stem cells/Proliferation/Differentiation/Basic ifbroblast growth factor/Vascular endothelial growth factor引用本文复制引用
杨炎歌,段淑荣..脑梗死后VEGF及bFGF对神经干细胞增殖分化的机制研究进展[J].中国卒中杂志,2016,11(8):704-708,5.基金项目
黑龙江省自然科学基金项目 ()