转化医学杂志2016，Vol.5Issue(4)：253-257,5.DOI:10.3969/j.issn.2095-3097.2016.04.019
干细胞衰老机制及应对策略的研究进展
The research progress of stem cell aging mechanisms and the solution
摘要
Abstract
Self-renewal and multilineage differentiation of stem cell are thought to be the ideal seed cell, with strong repair capacity for injured tissues. However, such as any other somatic cells, stem cell is aging upon a long-term culture, then it will affect the treatment of disease. So, in order to ensure the best treatment of stem cell for disease, it is necessary to understand stem cell aging mechanisms. This review discuss the aging mechanisms of stem cell mainly from the telomerase sys-tem, Wnt/β-catenin signaling pathways, oxidative stress and so on, then we want to find the solu-tion in order to achieve the goal of delaying stem cell senescence and even reversing the aging.关键词
干细胞/衰老/机制/延缓衰老Key words
Stem cell/Aging/Mechanisms/Anti-aging分类
生物科学引用本文复制引用
汪文婧,陈旭昕,韩志海..干细胞衰老机制及应对策略的研究进展[J].转化医学杂志,2016,5(4):253-257,5.基金项目
国家自然科学基金资助项目(81300050),海军总医院创新培育基金( CXPY201417) （81300050）
