川北医学院学报2016，Vol.31Issue(4)：448-451,4.DOI:10.3969/j.issn.1005-3697.2016.04.01
对比剂碘浓度在双源双能量CT检查中对血管和肝脏强化的影响
Effect of different iodine concentrations of contrast material on the vascu-lar and hepatic enhancement during dual-source dual-energy CT
摘要
Abstract
Objective:To compare vascular and parenchymal contrast enhancement in dual-energy CT of the liver using two contrast media with different iodine concentration (iopamidol 300 mgI /mL and 370 mgI /mL),use of a protocol with iodine dose adjus-ted for the patient’s body surface area com-(BSA;17.1 gI /m2 BSA)and fixed injection duration (25 s).Methods:300 patients were prospectively randomized into four groups.Patients in groups A and C received iopamidol with an iodine concentration of 300mg I /mL, B and D received iopamidol with an iodine concentration of 370mg I /mL respectively.Iodine dose was adjusted according to BSA,with a fixed injection duration of 25 s.Dual-energy acquisition mode was performed during late hepatic-arterial phase(A,B)and portal ve-nous phase(C,D).Enhancement of the abdominal aorta,liver and portal vein were compared between high-concentration contrast medi-um and low-concentration contrast medium at 80kVp,140kVp and color-coded iodine overlay images.The Mann-Whitney U test was used to enhance the difference between group.Results:At 80kVp,140kVp or color-coded iodine overlay images,the mean contrast en-hancement of the aorta was a trend towards higher contrast enhancement during the hepatic arterial phase,which was not statistically sig-nificant,when the higher concentration contrast medium was injected.And there was no significant difference between two iodine con-centration contrast medium for the mean contrast enhancement of the portal vein during the hepatic portal venous phase and for the mean contrast enhancement of the hepatic parenchyma during each acquisition phase (P >0.05).Conclusion:With fixed injection duration (25 s)and iodine load being tailored according to BSA,comparable contrast enhancement can be achieved with 300mg I /mL and 370mg I /mL being injected in liver enhanced DECT imaging.关键词
对比剂/对比强化/双能量CT/肝脏成像Key words
Contrast media/Contrast enhancement/Dual energy CT/Liver imaging分类
医药卫生引用本文复制引用
赵林伟,董国礼,杨国庆,赵秀华,冯敏..对比剂碘浓度在双源双能量CT检查中对血管和肝脏强化的影响[J].川北医学院学报,2016,31(4):448-451,4.基金项目
四川省卫计委科研课题 （）
