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转化生长因子-β1与表皮生长因子在成人增生性瘢痕中的表达及意义

黄克华 周国富 陈朗

川北医学院学报2016,Vol.31Issue(4):548-552,5.
川北医学院学报2016,Vol.31Issue(4):548-552,5.DOI:10.3969/j.issn.1005-3697.2016.04.027

转化生长因子-β1与表皮生长因子在成人增生性瘢痕中的表达及意义

Expression and significance of TGF-β1 and EGF in adult hypertrophic scar

黄克华 1周国富 2陈朗2

作者信息

  • 1. 重庆市渝北区人民医院烧伤整形科,重庆 401120
  • 2. 川北医学院附属医院烧伤整形科,四川 南充 637000
  • 折叠

摘要

Abstract

Objective:To investigate transforming growth factor-β1 (TGF-β1 )and epidermal growth facto (EGF)in adults hy-pertrophic scars occurred in possible role,to provide basis for clinical prevention.Methods:The expression of TGF-β1 and EGF in adult hypertrophic scar and adult normal skin was quantitatively detected by SP and ELISA methods.Results:TGF-β1 ,EGF in adults hyper-trophic scars showed high expression,both expressed in adult hyperplastic scar levels were positively correlated.Conclusion:TGF-β1 , EGF in adults hypertrophic scars showed high expression,TGF-β1 and EGF expression levels in adult hypertrophic scars were positively correlated,which provide new ideas for clinical prevention and treatment of skin hypertrophic scars.

关键词

成人增生性瘢痕/表皮生长因子/转化生长因子-β1

Key words

Adult hypertrophic scar/Epidermal growth factor/Transforming growth factor-β1

分类

医药卫生

引用本文复制引用

黄克华,周国富,陈朗..转化生长因子-β1与表皮生长因子在成人增生性瘢痕中的表达及意义[J].川北医学院学报,2016,31(4):548-552,5.

基金项目

四川省卫生发展研究中心项目 ()

川北医学院学报

OACSTPCD

1005-3697

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