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化疗药物渗漏性损伤治疗新方法的临床应用及相关机理

蒋红 杜华英 贾艾敏 姚亚希 杨明辉

川北医学院学报2016,Vol.31Issue(4):570-571,585,3.
川北医学院学报2016,Vol.31Issue(4):570-571,585,3.DOI:10.3969/j.issn.1005-3697.2016.04.033

化疗药物渗漏性损伤治疗新方法的临床应用及相关机理

Clinical application and related mechanism of new treatments for chemo-therapy extravasation injury

蒋红 1杜华英 2贾艾敏 3姚亚希 4杨明辉4

作者信息

  • 1. 川北医学院附属医院风湿免疫研究所,四川 南充 637000
  • 2. 川北医学院附属医院医学研究中心,四川 南充 637000
  • 3. 川北医学院附属医院烧伤科,四川 南充 637000
  • 4. 川北医学院附属医院医学研究中心,四川 南充 637000
  • 折叠

摘要

Abstract

Objective:To evaluate the clinical application and related mechanism of new treatments for chemotherapy extravasa-tion injury.Methods:100 cases of oncology patients with chemotherapy extravasation injury who were hospitalized during March 2012 and March 2015,were randomly divided into two groups.50 patients in the control group were given 2% anisodamine for local closure therapy while patients in the observation group were given 2% anisodamine combined with 1 % lidocaine.All the patients were given cold compress with sustained pressure for 1 day and subsequently hot compress.50% MgSO4 was used both in the cold compress and the hot compress.The clinical effect was observed between the two groups.Results:The total effective rate of observation group was sig-nificantly higher than that of the control group,the time of skin wound healing was significantly shorter than that of the control group,the difference was statistically significant.Conclusion:2% anisodamine combined with 1 % lidocaine can effectively treat chemotherapy ex-travasation injury.This therapy is worthy of clinical application and application.

关键词

化疗药物/渗漏性损伤/治疗方法/机理

Key words

Chemotherapy/Extravasation injury/Treatment/Mechanism

分类

医药卫生

引用本文复制引用

蒋红,杜华英,贾艾敏,姚亚希,杨明辉..化疗药物渗漏性损伤治疗新方法的临床应用及相关机理[J].川北医学院学报,2016,31(4):570-571,585,3.

川北医学院学报

OACSTPCD

1005-3697

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