磁共振成像2016，Vol.7Issue(8)：602-607,6.DOI:10.12015/issn.1674-8034.2016.08.009
动机对反应攻击的调制作用--基于静息态fMRI的个体差异研究
The effect of intentionality on reactive aggression：a rs-fMRI study on individual differences
摘要
Abstract
Objective:To study the neural basis of individual differences in the effect of other’s intentionality on individual’s reactive aggression, we used a variant of taylor aggression paradigm (TAP), with resting-state functional magnetic resonance imaging (rs-fMRI) technology.Materials and Methods:Our experiment recruited thirty healthy male volunteers. These participants played successive competitive reaction-time tasks with four opponents in turn and the loser who responded more slowly would be punished by the winner. The four opponents were comprised of intentional high-aggressive opponent, intentional low-aggressive opponent, unintentional high-aggressive opponent and unintentional low-aggressive opponent. The effect of other’s intentionality on individual’s reactive aggression (i.e. the effect of intentionality) was measured by the difference in punishment intensity which participant gave to the intentional high-aggressive opponent and unintentional high-aggressive opponent. The rs-fMRI data was processed using DPARSF toolbox. Then correlation analysis was conducted to examine the relationship between the effect of intentionality and ReHo values.Results:Signiifcant positive correlations between the effect of intentionality and ReHo values were observed in the temporo-parietal junction. Signiifcant negative correlations between the effect of intentionality and ReHo values were observed in thestriatum.Conclusion:The data indicates that temporo-parietal junction and striatum are involved in the effect of other’s intentionality on individual’s reactive aggression.关键词
反应攻击/动机/磁共振成像,功能/泰勒范式/局部一致性/颞顶联合区/纹状体Key words
Reactive aggression/Intentionality/Magnetic resonance imaging, functional/Taylor aggression paradigm/Regional homogeneity/Temporo parietal junction/Striatum分类
医药卫生引用本文复制引用
刘擘,陈卓,郑丽,李林,宁瑞鹏,郭秀艳..动机对反应攻击的调制作用--基于静息态fMRI的个体差异研究[J].磁共振成像,2016,7(8):602-607,6.基金项目
国家自然科学基金项目(编号31271090，71371180)；国家社会科学基金重点项目(编号14AZD106)；上海市自然科学基金项目(编号14ZR1411300)ACKNOWLEDGMENTS This research was supported by the National Natural Science Foundation of China (No.31271090,71371180) （编号31271090，71371180）
the Key Program of the National Social Science Foundation of China (No.14AZD106) and Shanghai Municipality Natural Science Fund (No.14ZR1411300) （No.14AZD106）
