南方医科大学学报2016，Vol.36Issue(8)：1129-1133,5.DOI:10.3969/j.issn.1673-4254.2016.08.18
数字三维技术联合纳米碳辅助导航在乳腺癌腔镜前哨淋巴结活检手术中的应用
Application of digital 3D technique combined with nanocarbon- aided navigation in endoscopic sentinel lymph node biopsy for breast cancer
摘要
Abstract
Objective To study the clinical value of digital 3D technique combined with nanocarbon-aided navigation in endoscopic sentinel lymph node biopsy for breast cancer. Methods Thirty-nine female patients with stage I/II breast cancer admitted in our hospital between September 2014 and September 2015 were recruited. CT lymphography data of the patients were segmented to reconstruct digital 3D models, which were imported into FreeForm Modeling Surgical System Platform for visual simulation surgery before operation. Endoscopic sentinel lymph node biopsy and endoscopic axillary lymph node dissection were then carried out, and the accuracy and clinical value of digital 3D technique in endoscopic sentinel lymph node biopsy were analyzed. Results The 3D models faithfully represented the surgical anatomy of the patients and clearly displayed the 3D relationship among the sentinel lymph nodes, axillary lymph nodes, axillary vein, pectoralis major, pectoralis minor muscle and latissimus dorsi. In the biopsy, the detection rate of sentinel lymph nodes was 100% in the patients with a coincidence rate of 87.18%(34/39), a sensitivity of 91.67%(11/12), and a false negative rate of 8.33%(1/12). Complications such as limb pain, swelling, wound infection, and subcutaneouseroma were not found in these patients 6 months after the operation. Conclusion Endoscopic sentinel lymph node biopsy assisted by digital 3D technique and nanocarbon-aided navigation allows a high detection rate of sentinel lymph nodes with a high sensitivity and a low false negative rate and can serve as a new method for sentinel lymph node biopsy for breast cancer.关键词
数字三维技术/淋巴造影/腔镜前哨淋巴结活检/腔镜腋窝淋巴结清扫Key words
digital 3D technique/CT lymphography/endoscopic sentinel lymph node biopsy/endoscopic lymph node dissection引用本文复制引用
张普生,罗云峰,俞金龙,方驰华,史福军,邓鉴文..数字三维技术联合纳米碳辅助导航在乳腺癌腔镜前哨淋巴结活检手术中的应用[J].南方医科大学学报,2016,36(8):1129-1133,5.基金项目
广东省科技计划项目（2013B021800308）；广东省科技计划项目（2014A020212495）；广东省医学科研基金项目（B2014258）；珠江医院留学归国基金 （）
