海南医学院学报2016，Vol.22Issue(16)：1880-1883,4.DOI:10.13210/j.cnki.jhmu.20160513.016
经颅多普勒超声评估大脑中动脉血流动力学参数与脑卒中后神经功能恢复的相关性
Correlation between middle cerebral arterial hemodynamic parameters assessed by tran-scranial doppler sonography and neural functional recovery after stroke
摘要
Abstract
Objective:To analyze the correlation between middle cerebral arterial hemodynamic parameters assessed by transcranial Doppler sonography and neural functional recovery after stroke.Methods:A total of 86 cases of hospitalized pa-tients with stroke were selected as observation group,107 cases of healthy subjects who received physical examination in our hospital during the same period were selected as control group,and both groups received the examination of middle cerebral ar-tery blood flow by transcranial Doppler sonography (TCD).According to the results of TCD,observation group were further divided into total occlusion group 21 cases,partial occlusion group 53 cases and non-occlusion group 12 cases.Middle cerebral arterial hemodynamic parameters,serum levels of neural function-related factors and serum levels of disease severity-related factors were compared among groups,and the correlation between the parameters of TCD and neural functional recovery after stroke was further analyzed.Results:Average Vs,Vm and Vd values of observation group were lower than those of control group,and as the degree of arterial occlusion increased,Vs,Vm and Vd values decreased (P <0.05);average NSE,S-100B, MBP,GFAP,Hcy,MMP-9,UA and Lp (a)values of observation group were higher than those of control group,BNDF was lower than that of control group,and as the degree of arterial occlusion increased in patients with stroke,the change tendency of the above factors increased (P <0.05);middle cerebral artery Vs,Vm and Vd values were negatively correlated with NSE, S-100B,MBP,GFAP,Hcy,MMP-9,UA and Lp (a)values,and positively correlated with BNDF value (P <0.05).Conclu-sions:Assessment of middle cerebral arterial hemodynamic parameters by transcranial Doppler sonography can accurately eval-uate long-term neural functional recovery of patients with stroke,and it has positive clinical significance.关键词
脑卒中/大脑中动脉/神经功能/多普勒超声Key words
Stroke/Middle cerebral artery/Neural function/Doppler sonography分类
医药卫生引用本文复制引用
吕晓云..经颅多普勒超声评估大脑中动脉血流动力学参数与脑卒中后神经功能恢复的相关性[J].海南医学院学报,2016,22(16):1880-1883,4.基金项目
陕西省科学技术计划资助项目(2012K06-14)[Foundation Project]:It was supported by Science and Technology Plan Project of Shaanxi Province (2012K06-14)． （2012K06-14）
