河北医学2016，Vol.22Issue(8)：1249-1251,3.DOI:10.3969/j.issn.1006-6233.2016.08.007
依达拉奉对急性脑梗死患者神经功能缺损及日常生活活动能力恢复的影响
Effects of Edaravone on the Recovery of Activities of Daily Living and Neurologic Impairment in Patients with Acute Cerebral Infarction
摘要
Abstract
Objective: To investigate the efficacy of edaravone in treatment of acute cerebral infarction , and to promote the recovery of activities of daily living and neurologic impairment .Methods: A total of 80 pa-tients were randomly divided into observation group and control group , with 40 patients in each group.The pa-tients of both groups were given conventional therapies , while the patients of the observation group given edar -avone additionally, and the nerve function and viability after 7d and 14d of treatment were evaluated by China stroke scale (CSS) and ADL evaluation form (Barthel index), respectively.Results:On admission, the two groups had insignificantly different CSS and Barthel index scores (P>0.05); after 7d and 14d of treatment, both groups had significantly decreased CSS scores and significantly increased Barthel index scores compared with those on admission, but the observation group had significantly greater improving extents (P<0.05).After 2 courses of treatment, In the observation group, 16 patients were cured, 13 were responsive to the therapy excellently, 8 were improved, and 3 were unresponsive to the therapy ; while of the control group, 8 patients were cured, 12 were responsive to the therapy excellently , 14 were improved, and 6 were unresponsive to the therapy; and the differences were statistically significant (P<0.05).Conclusion: Application of edaravone in patients with acute cerebral infarction can significantly improve nerve function and promote the recovery of ac -tivities of daily living (ADL) and improve the quality of life.关键词
急性脑梗死/依达拉奉/神经功能缺损/日常生活活动能力Key words
Acute cerebral infarction/Edaravone/Neurologic impairment/Activity of daily liv-ing引用本文复制引用
潘江,冯华明..依达拉奉对急性脑梗死患者神经功能缺损及日常生活活动能力恢复的影响[J].河北医学,2016,22(8):1249-1251,3.基金项目
四川省科技厅资助项目， （）
