河北医学2016，Vol.22Issue(8)：1265-1267,3.DOI:10.3969/j.issn.1006-6233.2016.08.013
噻托溴铵联合沙美特罗替卡松粉吸入治疗慢性阻塞性肺疾病稳定期的疗效
Tiotropium Combined with Salmeterol and Fluticasone Propionate Powder Inhalation in Treating Patients with COPD in Stable Stage
摘要
Abstract
Objective: To study the effect of tiotropium combined with salmeterol and fluticasone propi -onate powder inhalation in the treatment of patients with chronic obstructive pulmonary disease (COPD) in stable stage.Methods: 116 cases of patients with stable COPD treated in our hospital from September 2012 to September 2014 were selected as objects.According to the digital method, 116 patients were randomly divided into observation group and control group , with 58 cases in each group, the control group was given with salme -terol and fluticasone propionate powder , patients in the observation group on the basis of it another given tiotropium for treatment, compared the efficacy of the two groups, FEV1 and FVC levels in the two groups be-fore and after treatment, and two groups after the treatment of drug adverse reactions .Results:The total effec-tive rate of observation group was 98.28% (57/58), which was significantly higher than the control group of 84.48% (49/58), the difference was statistically significant (P <0.05).Compared with the FEV1 and FVC levels in the two groups before treatment, there was no statistically significant difference (P >0.05).Observa-tion group of FEV1 and FVC levels after treatment were significantly higher than the control group , the differ-ence was statistically significant (P <0.05).The total incidence of complications of the observation group was 25.86% (15/58), and 12.07% (7/58) in the control group, there was no statistically significant difference (P >0.05).Conclusion: Combined with tiotropium bromide and salmeterol and fluticasone propionate in the treatment of COPD patients, curative effect is better, and the safety is high, is worth popularizing in the clini-cal course of treatment.关键词
噻托溴铵/沙美特罗替卡松粉/吸入治疗/慢性阻塞性肺疾病Key words
Tiotropium bromide powder/Salmeterol and fluticasone propionate/Inhalation treat-ment/Chronic obstructive pulmonary disease引用本文复制引用
张建新,陈希妍,吴畏,李广鹏,郝同琴..噻托溴铵联合沙美特罗替卡松粉吸入治疗慢性阻塞性肺疾病稳定期的疗效[J].河北医学,2016,22(8):1265-1267,3.基金项目
河南省医学科技攻关计划项目， （）
