哈尔滨医药2016,Vol.36Issue(4):415-416,2.
抗结核药物对乙肝病毒感染肺结核患者发生肝损害的临床分析
Clinical Analysis of the Occurrence of Anti-tuberculosis Drugs for TB Patients Infected With the Hepatitis B Virus Liver Damage
唐颖 1段义军 1刘仕会 1谢兵1
作者信息
- 1. 云南省普洱市疾病预防控制中心,云南普洱665000
- 折叠
摘要
Abstract
Objective Analysis of clinical cases occur in patients with pulmonary TB drugs HBV infection of liver damage. Methods 61 cases of hepatitis B virus markers positive TB patients(study group) and 64 cases of hepatitis B virus markers nega-tive tuberculosis patients (control group) were taken to the same anti-tuberculosis drugs, compared between the two groups of pa-tients the incidence of liver damage, liver before and after treatment function index (ALT, AST, TBIL) changes and liver dysfunc-tion appear time and recovery time. Results Observed incidence of liver dysfunction was significantly higher (P<0.05);after treat-ment observation group liver function (ALT, AST, TBIL) was significantly higher than the control group (P<0.05); observation of liver dysfunction appear an earlier time, and recovery time than the control group later (P<0.05).Conclusion Anti-TB drugs for TB patients infected with the hepatitis B virus cause significant liver damage, so TB should be checked prior to drug treatment of hepatitis B virus markers, Liver drug use during treatment, and should always check liver function, so early detection, early diag-nosis, early treatment, improve the cure rate of tuberculosis.关键词
抗结核药物/肺结核/乙肝病毒/肝损害Key words
TB drugs/Tuberculosis/Hepatitis B virus/Liver damage分类
医药卫生引用本文复制引用
唐颖,段义军,刘仕会,谢兵..抗结核药物对乙肝病毒感染肺结核患者发生肝损害的临床分析[J].哈尔滨医药,2016,36(4):415-416,2.