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抗结核药物对乙肝病毒感染肺结核患者发生肝损害的临床分析

唐颖 段义军 刘仕会 谢兵

哈尔滨医药2016,Vol.36Issue(4):415-416,2.
哈尔滨医药2016,Vol.36Issue(4):415-416,2.

抗结核药物对乙肝病毒感染肺结核患者发生肝损害的临床分析

Clinical Analysis of the Occurrence of Anti-tuberculosis Drugs for TB Patients Infected With the Hepatitis B Virus Liver Damage

唐颖 1段义军 1刘仕会 1谢兵1

作者信息

  • 1. 云南省普洱市疾病预防控制中心,云南普洱665000
  • 折叠

摘要

Abstract

Objective Analysis of clinical cases occur in patients with pulmonary TB drugs HBV infection of liver damage. Methods 61 cases of hepatitis B virus markers positive TB patients(study group) and 64 cases of hepatitis B virus markers nega-tive tuberculosis patients (control group) were taken to the same anti-tuberculosis drugs, compared between the two groups of pa-tients the incidence of liver damage, liver before and after treatment function index (ALT, AST, TBIL) changes and liver dysfunc-tion appear time and recovery time. Results Observed incidence of liver dysfunction was significantly higher (P<0.05);after treat-ment observation group liver function (ALT, AST, TBIL) was significantly higher than the control group (P<0.05); observation of liver dysfunction appear an earlier time, and recovery time than the control group later (P<0.05).Conclusion Anti-TB drugs for TB patients infected with the hepatitis B virus cause significant liver damage, so TB should be checked prior to drug treatment of hepatitis B virus markers, Liver drug use during treatment, and should always check liver function, so early detection, early diag-nosis, early treatment, improve the cure rate of tuberculosis.

关键词

抗结核药物/肺结核/乙肝病毒/肝损害

Key words

TB drugs/Tuberculosis/Hepatitis B virus/Liver damage

分类

医药卫生

引用本文复制引用

唐颖,段义军,刘仕会,谢兵..抗结核药物对乙肝病毒感染肺结核患者发生肝损害的临床分析[J].哈尔滨医药,2016,36(4):415-416,2.

哈尔滨医药

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