检验医学与临床2016，Vol.13Issue(16)：2258-2260,3.DOI:10.3969/j.issn.1672-9455.2016.16.009
肥胖与良性前列腺增生的相关性研究
Research of the correlation between obesity and benign prostatic hyperplasia
摘要
Abstract
Objective To investigate the correlation between obesity and benign prostatic hyperplasia (BPH) ,and explore the pathogenesis of BPH .Methods A total of 120 patients with BPH were collected and divided into the normal group ,overweight group and obesity group according to the BMI .Indexs of fasting blood glucose (FBG) ,triglyceride(TG) ,high density lipoprotein cholesterol (HDL-C) ,interleukin 6 (IL-6) ,prostate volume(PV ) ,maximal urinary flow rate (Qmax ) and international prostate symptom score (IPSS) .And the correlation between obesity and BPH indexes were analyzed by statistical method .Results In the overweight group and obesity group ,the level of IPSS ,PV and IL-6 were significantly higher than those in the normal group (P<0 .05) .The score of Qmax was significantly lower than that in the normal group (P< 0 .05) .The study revealed a positive correla-tion between IPSS ,PV ,IL-6 and BMI (r= 0 .486 ,0 .518 and 0 .729 ,P< 0 .01) .And Qmax was negatively correlated with BMI (r=- 0 .391 ,P< 0 .01) .Conclusion Obesity is closely correlated with the occurrence and development of BPH ,IL-6 may play an im-portant role in the pathological and physiological process of BPH .关键词
肥胖/良性前列腺增生/相关性Key words
obesity/benign prostatic hyperplasia/correlation引用本文复制引用
张杰,潘永军,黄捷,陈雄,张雄..肥胖与良性前列腺增生的相关性研究[J].检验医学与临床,2016,13(16):2258-2260,3.基金项目
重庆市卫生计生委医学科研项目（20142177）。 （）
