摘要
Abstract
Objective To investigate the clinic effects of combined treatment of octreotide and sodium aescinate in patients with mild acute pancreatitis(MAP) .Methods A total of 84 MAP patients ,treated in this hospital from Jun .2014 to Jun .2015 ,were di-vided into observation group(42 cases) and control group(42 cases) .Patients in control group were treated with octreotide on the basis of routine treatment .Patients in observation group were treated with sodium aescinate on the basis of treatment of control group .Course of treatment was one week .Therapeutic effects ,improvement of clinical symptom ,levels of laboratory parameters and adverse reaction were compared .Results The total efficiency of observation group was 92 .9% ,significantly higher than the 76 .2% of control group(P< 0 .05) .The nausea and vomiting disappeared time ,bloating and abdominal pain relief time ,the first defecation time ,hospitalization time ,serum amylase ,urine amylase ,C-reaction protein ,tumor necrosis factor-ɑ of the observation group were significantly less than control group after the treatment (P < 0 .05) .Incidence of gastrointestinal discomfort ,liver and kidney dysfunction ,pancreatic pseudocyst ,abdominal pain and diarrhea were without significant differences between the two groups (P> 0 .05) .Conclusion Combined treatment of octreotide and sodium aescinate in MAP patients could be with exact effects ,effec-tively reduce the secretion of inflammatory cytokines ,the levels of blood and urine amylase and C-reaction protein ,improve clinical symptoms ,with fewer side effects ,which might be worthy of promotion .关键词
轻度急性胰腺炎/血淀粉酶/尿淀粉酶/C-反应蛋白Key words
mild acute pancreatitis/serum amylase/urine amylase/C-reactive protein
