检验医学与临床2016，Vol.13Issue(16)：2286-2287,2.DOI:10.3969/j.issn.1672-9455.2016.16.019
血清骨膜蛋白对急性心肌梗死的诊断价值研究
Diagnostic value of serum periostin for patients with acute myocardial infarction
潘露 1闵瑶2
作者信息
- 1. 四川省成都市第五人民医院检验科 611130
- 2. 重庆东华医院检验科 400032
- 折叠
摘要
Abstract
Objective To evaluate the diagnostic values of serum periostin for patients with acute myocardial infarction(AMI) . Methods Enzyme linked immunosorbent assay(ELISA) was performed for the measurement of serum periostin in 76 AMI patients and 93 controls ,and serum cardiac troponin I(cTnI) and creatine kinase isoenzyme MB(CK-MB) were measured by electrochemilu-minescence assay .Results Concentrations of serum periostin ,cTnI and CK-MB in AMI group were higher than control group(P<0 .05) .The optimal cutoff value of serum periostin for the diagnosis of AMI was 22 .9 ng/mL ,with 0 .86 of the area under receiver operating characteristic curve ,84 .2% of the sensitivity and 87 .8% of the specificity .The correlation coefficients of serum periostin with cTnI and CK-MB were 0 .261 and 0 .228(P < 0 .05) ,respectively .Conclusion Periostin could be used for the diagnosis of AMI ,with significant correlation with cTnI and CK-MB ,and might be a risk factor for AMI .关键词
急性心肌梗死/骨膜蛋白/心肌肌钙蛋白I/肌酸激酶同工酶Key words
acute myocardial infarction/periostin/cTnI/CK-MB引用本文复制引用
潘露,闵瑶..血清骨膜蛋白对急性心肌梗死的诊断价值研究[J].检验医学与临床,2016,13(16):2286-2287,2.
