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首页|期刊导航|四川医学|利妥昔单抗注射液联合化疗治疗B细胞非霍奇金淋巴瘤疗效观察

利妥昔单抗注射液联合化疗治疗B细胞非霍奇金淋巴瘤疗效观察

景莉

四川医学2016,Vol.38Issue(8):916-919,4.
四川医学2016,Vol.38Issue(8):916-919,4.DOI:10.16252/j.cnki.issn1004-0501-2016.08.024

利妥昔单抗注射液联合化疗治疗B细胞非霍奇金淋巴瘤疗效观察

Clinical Observation of B Cell Non-hodgkin’s Lymphoma Treated with Rituxan Injection and Chemotherapy

景莉1

作者信息

  • 1. 西南医科大学附属医院血液科,四川 泸州646000
  • 折叠

摘要

Abstract

Objective Analysis and research of the clinical observation of patients with B cell non-hodgkin’s lymphoma treated with rituxan injection and chemotherapy. Methods 64 patients with B cell non-hodgkin’s lymphoma participated in this study were diagnosed from 2013 to 2015 in our hospital. According to the different treatments, patients were randomly divided into 2 groups. The control group (32 cases) :the therapy was simple CHOP chemotherapy;the experimental group (32 cases) :was given the rituxan injection and chemotherapy. All the patients were given 4 continuous cycles of treatment , then clinical therapeutic effects were compared between two groups and so did the different treatment cycle of the total white blood cells and lymphocyte count and lymphocyte proportion . Results After treatment, compared with before treatment, both therapies had certain therapeutic effect, but 90. 62% of the total effective rate of the experimental group is obviously higher than the control group(71. 88%), P<0. 05, the difference was statistically significant. The indicators like total white blood cells of two groups were both decreased, but the clinical effect of the experimental group compared with control group was obvious. But on the occurrence of adverse reaction, there was no ob-vious difference between the two groups, that was no significant difference. Conclusion In the treatment of patients with B cell non-hodgkin’s lymphoma, the clinical curative effect of ituxan injection and chemotherapy was obvious than the chemotherapy only and that combining therapy can be widely applied in clinic.

关键词

利妥昔单抗注射液/化疗/非霍奇金淋巴瘤/临床效果

Key words

rituxan injection/chemotherapy/non-hodgkin’s lymphoma/clinical observation

分类

医药卫生

引用本文复制引用

景莉..利妥昔单抗注射液联合化疗治疗B细胞非霍奇金淋巴瘤疗效观察[J].四川医学,2016,38(8):916-919,4.

四川医学

OACSTPCD

1004-0501

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