肿瘤预防与治疗2016，Vol.29Issue(4)：205-209,5.DOI:10.3969/j.issn.1674-0904.2016.04.003
宝石 CT 能谱成像在乳腺浸润性导管癌腋窝转移淋巴结诊断中的初步应用
Preliminary Study of Gemstone Spectral Imaging in the Diagnosis of Axillary Lymph Nodes Metastasis in Patients with Infiltrating Ductal Breast Carcinoma
黄丹 1刘启榆 1何川东 2周莹 2林华 2陈娇 2管彬 2王晋秋 2廖丽萍2
作者信息
- 1. 西南医科大学附属医院放射科，四川 泸州 646000
- 2. 绵阳市中心医院放射科，四川 绵阳 621000
- 折叠
摘要
Abstract
Objective:To evaluate the clinical feasibility of gemstone spectral imaging(GSI)in the diagnosis of axillary lymph nodes metastasis in patients with infiltrating ductal breast carcinoma.Methods:Thirty-two cases of patho-logically proven infiltrating ductal breast carcinoma from Feb.2013 to Dec.2014 were included in this study.All cases un-derwent GSI scan in lateral artery phase (33s).Images were retrospectively analyzed using GSI viewer on ADW 4.6 work station.The axillary lymph nodes were classified as metastatic group (n =15)or non-metastatic group (n =62)according to the pathological diagnosis.The KeV-CT value curve was generated by the computer automatically,the iodine-based value and CT value of each lymph nodes and the corresponding strata of the artery were recorded.The slope of KeV-CT value curve [defined as:K =(HU40KeV HU70KeV)/30],normalized iodine-based value (lymph node iodine-based value /arterial iodine-based value),normalized CT values (lymph node CT value /arterial CT value)under different KeVs were compared between the metastatic and non-metastatic lymph nodes.Spss17.0 software was used for analysis and P <0.05 was considered statistically different.Results:The slope of KeV-CT value curve of axillary metastatic lymph nodes was sig-nificantly different from that of non-metastatic lymph nodes (P <0.05)in 40 ~70KeV area.The Iodine-based value and the normalized Iodine-based value of metastatic lymph nodes were significantly lower than those of the non-metastatic group (P <0.05).No statistically significant difference was found of the normalized CT value between the metastatic and non-metastatic group.When the threshold of the slope of KeV-CT value curve was set at 3.92,the sensitivity and specificity were 77.4% and 71.4%,respectively.When the threshold of the Iodine-based value was set at 19.44,the sensitivity and specificity were 73.3% and 72.6%,respectively.While sensitivity and specificity for the normalized Iodine-based value were 82.3% and 80.0%,respectively when the threshold of the nomarlized Iodine-based value was set at 0.1677.Conclu-sion:GSI as a new non-invasive examination,is an important way for the detection of axillary lymph nodes metastasis in patients with infiltrating ductal breast carcinoma.关键词
能谱 CT 成像/乳腺浸润性导管癌/转移/非转移淋巴结Key words
Gemstone Spectral Imaging/Infiltrating Ductal Breast Carcinoma/Metastatic /Non-metastatic Lymph Node分类
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黄丹,刘启榆,何川东,周莹,林华,陈娇,管彬,王晋秋,廖丽萍..宝石 CT 能谱成像在乳腺浸润性导管癌腋窝转移淋巴结诊断中的初步应用[J].肿瘤预防与治疗,2016,29(4):205-209,5.
