山西医科大学学报2016，Vol.47Issue(8)：760-763,4.DOI:10.13753/j.issn.1007-6611.2016.08.019
妊娠合并系统性红斑狼疮患者孕期狼疮病情活动与妊娠结局的关系
A retrospective study of pregnancy outcomes in patients with systemic lupus erythematosus
王慧英 1叶艺璇 2屠京慧 1于莎莎 1赵锦松3
作者信息
- 1. 首都医科大学附属北京世纪坛医院产科，北京 100038
- 2. 北京大学医学部公共卫生学院
- 3. 首都医科大学附属北京世纪坛医院风湿免疫科
- 折叠
摘要
Abstract
Objective To explore the maternal and fetal outcomes of pregnancy in patients with systemic lupus erythematosus( SLE) . Methods The clinical data of 20 cases of pregnancy complicated with SLE were retrospectively analyzed. Twenty pregnant women complicated with SLE were divided into active phase(n=13) and inactive phase(n=7) according to the progression condition of SLE. The maternal and infantile complications and pregnancy outcomes in the two groups were compared and analyzed. Results The rate of full-term birth in pregnancy with inactive SLE was significantly higher than that in pregnancy with active SLE(P<0. 05), and the incidence of prematurity in pregnancy with inactive SLE was significantly lower than that in pregnancy with active SLE(P<0. 05). The fetal birth gestational age and body weight in pregnancy with inactive SLE were significantly higher than that in pregnancy with active SLE(P<0. 01), and the incidence of complications in pregnancy with inactive SLE was significantly lower than that in pregnancy with active SLE(P<0. 01). No preeclampsia occurred in inactive group, while 10 cases of preeclampsia were observed in active group, and there was significant difference between two groups(P<0. 01). Conclusion The incidence rate of adverse pregnancy outcome as well as the pregnancy complications in pregnant women complicated with SLE during active phase is relatively high, thus the guidance during gestational period should be strengthened among pregnant women complicated with SLE.关键词
妊娠/系统性红斑狼疮/妊娠结局Key words
pregnancy/systemic lupus erythematosus/pregnancy outcome分类
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王慧英,叶艺璇,屠京慧,于莎莎,赵锦松..妊娠合并系统性红斑狼疮患者孕期狼疮病情活动与妊娠结局的关系[J].山西医科大学学报,2016,47(8):760-763,4.
