现代妇产科进展2016，Vol.25Issue(8)：593-595,3.DOI:10.13283/j.cnki.xdfckjz.2016.08.009
阜阳地区妊娠期亚临床甲减诊断标准和筛查策略的探讨
Study of two different criteria and screening strategies for subclinical hypothyroidism in ;pregnant women in Fuyang Area
王常宏 1周营营 2宛杨 3丛林3
作者信息
- 1. 安徽医科大学第一附属医院产前诊断中心，合肥 230022
- 2. 阜阳市人民医院，阜阳 236000
- 3. 阜阳市人民医院，阜阳 236000
- 折叠
摘要
Abstract
Objective:To investigate two different criteria and screening strategies for subclinical hypothyroidism in pregnant women in Fuyang area. Methods:The study was sur-veyed in population taking their prenatal care from Apr. 2015 to Sep. 2015 at the Fuyang People 's Hospital. There were 2421 pregnant women enrolled in this study. The clinical history of all these women was collected and they were divided into high-risk and low-risk groups. Their ser-um TSH、FT4、FT3、TPOAb、TGAb were recorded and analyzed according to the following two criteria:(1) foreign criterion:according to 2011 ATA guideline;(2) national criterion:accord-ing to 2012 Chinese guidelines for the diagnosis and treatment of thyroid disease during preg-nancy and postpartum. Morbidity rates of subclinical hypothyroidism were compared between different diagnosis and groups. Results:Morbidity rates of subclinical hypothyroidism with na-tional criterion was 3. 8%,lower than 18. 7% with foreign criterion(P<0. 001). In high risk group,morbidity rates of subclinical hypothyroidism with national criterion was 5. 5%,with for-eign criterion was 24. 1%,which was higher than that in low risk group with no statistical sig-nificance(P>0. 05). According to national criterion,if only tested High-risk groups,misdiagno-sis rate of pregnancy with subclinical hypothyroidism would be 82 . 7%. Conclusions:In diagno-sis subclinical hypothyroidism in pregnant women in Fuyang area, morbidity rate with foreign criterion is higher than with national criterion. If only test high-risk groups,misdiagnosis rate of pregnancy with subclinical hypothyroidism may be higher.关键词
妊娠期/亚临床甲减/诊断标准/筛查策略Key words
Pregnancy/Subclinical hypothyroidism/Diagnosis criteria/Screening strat-egies分类
医药卫生引用本文复制引用
王常宏,周营营,宛杨,丛林..阜阳地区妊娠期亚临床甲减诊断标准和筛查策略的探讨[J].现代妇产科进展,2016,25(8):593-595,3.
