中国组织工程研究2016，Vol.20Issue(33)：4957-4962,6.DOI:10.3969/j.issn.2095-4344.2016.33.013
肝移植及腹部多器官移植手术的成分输血
Transfusion of blood components in liver transplantation and abdominal multiple organ transplantation
摘要
Abstract
BACKGROUND:The liver transplantation and abdominal multiple organ transplantation are complicated surgeries, characterized by massive blood loss and high blood transfusion requirements. OBJECTIVE:To explore the characteristics of blood loss and blood transfusion in liver transplantation and abdominal multiple organ transplantation and post-operative survival rate. METHODS:Clinical data from 192 patients were retrospectively analyzed, including blood transfusion data with the first 24 hours after surgery and post-operative survival rate. RESULTS AND CONCLUSION:These 192 patients included 177 patients receiving liver transplantation, 2 patients receiving liver and kidney transplantation and 13 patients receiving abdominal multiple organ transplantation. The average intra-operative blood loss of each patient was (2 401.5±3 239.5) mL. The average infusion of red blood cel s, platelet, cryoprecipitate and frozen plasma of each patient at the first 24 hours after surgery was (11.3±11.9), (0.8±0.9), (10.7±11.7) U and (2 805.5±1 393.1) mL, respectively. Al kinds of blood infusion in the liver cancer group were obviously less than those in the hepatic failure group. The infusion of cryoprecipitate and frozen plasma in the cirrhosis group was obviously less than that in the hepatic failure group, but the infusion of platelet in the cirrhosis group was significantly more than that in the liver cancer group. The infusion of red blood cel s from July 2013 to June 2015 was significantly less than that from July 2012 to June 2013. The blood loss, infusion of red blood cel s and frozen plasma in the liver transplantation group of cirrhosis were significantly more than those in the abdominal multiple organ transplantation group of cirrhosis (al P<0.05). In conclusion, diagnosis of liver diseases, and the maturity of surgery exert an effect on the blood loss and blood infusion. As the development of liver transplantation and abdominal multiple organ transplantation, both the blood loss and blood infusion are decreased. Besides, compared with liver transplantation, the blood loss and blood infusion show no increase in the abdominal multiple organ transplantation.关键词
组织构建/组织工程/肝移植/腹部多器官移植/失血/红细胞输注量/血小板输注量/冷沉淀输注量/血浆输注量/肝癌/肝硬化/存活期/国家自然科学基金分类
医药卫生引用本文复制引用
林静霞,苏凡,罗宏山..肝移植及腹部多器官移植手术的成分输血[J].中国组织工程研究,2016,20(33):4957-4962,6.基金项目
广东省自然科学基金项目(2015A030306025)；国家自然科学基金项目(81302549)@@@@the Natural Science Foundation of Guangdong Province, No.2015A030306025 （2015A030306025）
the National Natural Science Foundation of China, No.81302549 （）
