现代医药卫生2016，Vol.32Issue(16)：2496-2497,2500,3.DOI:10.3969/j.issn.1009-5519.2016.16.017
增强型体外反搏治疗心绞痛的作用机制及其对炎症因子的影响
Mechanism of EECP in treatment of angina pectoris and its influence on inflammatory factors
刘盼 1郑文武 1蒋灿 1黄冬梅 1刘茜 1李丹 1廖双华1
作者信息
- 1. 西南医科大学附属医院心内科，四川 泸州 646000
- 折叠
摘要
Abstract
Objective To investigate the action mechanism of the enhanced external counter pulsation (EECP) for treat-ing angina pectoris. Methods Fifty-six patients with chronic ischemic angina pectoris in our hospital from January 2014 to September 2015 were selected and randomly divided into the treatment group(39 cases) and the control group(17 cases). The two groups were performed the routine therapy and examinations. The patients in the treatment group were performed EECP accompa-nied by the medical staff in the whole process. ELISA was adopted to detect MMP-9 and TNF-αlevels. The curative effects of the two groups were comparatively analyzed. Results The effective rate after therapy in the treatment group was 92.3%(36/39), which was higher than 41.2%(7/17) in the control group,the difference was statistically significant(P<0.01);the MMP-9 and TNF-αlevels after treatment in the two groups were superior to those before treatment ,moreover the treatment group was superior to the control group,the difference was statistically significant(P<0.05). Conclusion The EECP therapy can decrease the levels of TNF-αand MMP-9 and improve the symptoms of angina pectoris.关键词
反搏动术/心绞痛/基质金属蛋白酶类/肿瘤坏死因子α/炎症Key words
Counterpulsation/Angina pectoris/Matrix metalloproteinases/Tumor necrosis factor-alpha/Inflammation引用本文复制引用
刘盼,郑文武,蒋灿,黄冬梅,刘茜,李丹,廖双华..增强型体外反搏治疗心绞痛的作用机制及其对炎症因子的影响[J].现代医药卫生,2016,32(16):2496-2497,2500,3.
