刑事技术2016，Vol.41Issue(4)：292-295,4.DOI:10.16467/j.1008-3650.2016.04.009
胺基纳米磁珠提取血液中3种毒品
Using Amino-modiifed Nano-magnetic Beads to Extract Three Drugs from Human Blood
摘要
Abstract
ABSTRACT:A new method has been developed with amino-modiifed nano-magnetic beads to extract methamphetamine, morphine and ketamine from human blood. The amino nano-magnetic beads, generated through combination of diethylamine with magnetic powder, were used to extract drugs from human blood. The GC/MS results showed that the produced beads effectively enriched the drugs in blood, with a recovery rate higher than 70 %. On average, the enrichment ratio was greater than 1:30. All of the important parameters were studied at the extraction strength, pH value, eluent consumption, standard curve, detection limit as well as the intra- and inter-day precisions, indicating that a higher extraction can be reached upon the employment of vortex, pH greater than 7 and the consumed elution at 80 μL. For GC/MS analysis, the linear range was from 0.5 to 10.0 μg/mL, correlation coefifcients (r) were 0.9826,0.9526 and 0.9914, and the detective limits were individually 0.062, 0.093 and 0.041μg/mL, respectively. The intra- and inter-day precisions were both less than 6.0 %. This method is of high enrichment efifciency and short adsorption time, capable of improving the detection sensitivity of drugs in blood.关键词
胺基纳米磁珠/提取/血液/毒品Key words
amino-modiifed nano-magnetic beads/extraction/human blood/drugs分类
社会科学引用本文复制引用
杨丽君,郭鹏,任周阳,谢文林..胺基纳米磁珠提取血液中3种毒品[J].刑事技术,2016,41(4):292-295,4.基金项目
公安部科技强警基础工作专项项目 （）
