中国病理生理杂志2016，Vol.32Issue(8)：1478-1483,6.DOI:10.3969/j.issn.1000-4718.2016.08.024
线粒体生成与脑缺血再灌注损伤的研究进展
Research progress of mitochondrial biogenesis and cerebral ischemia/reperfusion injury
摘要
Abstract
Mitochondria are important intracellular energy supply organelles .As semi-autonomous organelles , the mitochondrial biogenesis , damage and clearance were the dynamic processes , which are dual-regulated by mitochondrial genes and nuclear genes , and maintain mitochondrial homeostasis according to the needs of the cells for energy .Recent studies provide evidence that the disorder of mitochondrial biogenesis in the neurons participates in the pathological process after cerebral ischemia/reperfusion, resulting in metabolic disturbance and cell apoptosis .This paper reviews the research progress of mitochondrion and cerebral ischemia/reperfusion injury .关键词
线粒体生成/脑缺血/再灌注损伤Key words
Mitochondrial biogenesis/Cerebral ischemia/Reperfusion injury分类
医药卫生引用本文复制引用
王来,祝世功..线粒体生成与脑缺血再灌注损伤的研究进展[J].中国病理生理杂志,2016,32(8):1478-1483,6.基金项目
国家自然科学基金资助项目（No．81471254；No．81171081）；河南省高等学校重点科研项目 （）
