中国普通外科杂志2016,Vol.25Issue(8):1198-1202,5.DOI:10.3978/j.issn.1005-6947.2016.08.019
慢性乙型肝炎病毒感染与肝内胆管细胞癌发生和预后的关系研究进展
Relations of hepatitis B virus infection with occurrence and prognosis of intrahepatic cholangiocarcinoma:recent research progress
JEONG Seogsong 1顾劲扬(综述) 1夏强(审校)1
作者信息
- 1. 上海交通大学医学院附属仁济医院 肝脏外科,上海 200127
- 折叠
摘要
Abstract
Intrahepatic cholangiocarcinoma (ICC) arising from the epithelial cells of the second order bile ducts and their branches, is one of the liver cancers with high degree of malignancy and poor prognosis. Lymph node metastasis is the most important factor affecting the prognosis of ICC patients. Recently, many studies indicated that hepatitis B virus (HBV) is an independent risk factor for ICC, and the clinical manifestations in patients with HBV-associated ICC are similar to those with hepatocellular carcinoma. Further, the latest studies demonstrated that the prognosis in HBV-positive ICC patients is better than that in HBV-negative patients, and HBV-positive ICC patients have a relatively low rate of lymph node metastasis. hTus, further insight into the actions of HBV on the pathogenesis and outcomes of ICC is of great clinical signiifcance.关键词
胆管上皮癌/胆管,肝内/乙型肝炎病毒/淋巴转移/预后/综述文献Key words
Cholangiocarcinoma/Bile Ducts, Intrahepatic/Hepatitis B virus, Lymphatic Metastasis/Prognosis/Review分类
医药卫生引用本文复制引用
JEONG Seogsong,顾劲扬(综述),夏强(审校)..慢性乙型肝炎病毒感染与肝内胆管细胞癌发生和预后的关系研究进展[J].中国普通外科杂志,2016,25(8):1198-1202,5.