中国药房2016，Vol.27Issue(23)：3177-3180,4.DOI:10.6039/j.issn.1001-0408.2016.23.04
贝叶斯混合处理比较法在药物经济学评价中的应用
Application of Bayesian Mixed Treatment Comparison Method in Pharmacoeconomics Evaluation
摘要
Abstract
OBJECTIVE:To explore the basic principles,advantages and application prospects of Bayesian mixed treatment comparison (MTC),and provide theoretic support for making reasonable decisions of pharmacoeconomics. METHODS:The prob-lems existing in model and method that had been used in the study of pharmacoeconomics as starting point,literature research was used to sort out the domestic development and applications of MTC and study its application and development prospect. RESULTS &CONCLUSIONS:The evaluation methods of pharmacoeconomics play an important role in selection of essential medicines,medi-care insurance directory medicines,basic health and basic public health programs,the results directly affect the total effective rate of medical resources’configuration. The current research models cannot effectively solve the problem,for example,decision tree model is difficult to make evaluation of long-term treatment;Markov model and the use of multiple attribute utility theory are restricted by the model parameters;discrete event simulation is limited because it depends on the epidemiological study and clinical trial. MTC, an extension approach of the traditional Meta-analysis,is an effective new method developed recently to analyze and compare the di-rect or indirect evidence of several different clinical treatment factors in order to make a comprehensive evaluation of the various inter-ventions in the absence of evidence support. So the MTC can make up for the limitation of current evaluation methods.关键词
贝叶斯混合处理比较法/药物经济学评价/应用Key words
Bayesian mixed treatment comparison method/Pharmacoeconomics evaluation/Application分类
医药卫生引用本文复制引用
师宇,饶惠霞,翁开源..贝叶斯混合处理比较法在药物经济学评价中的应用[J].中国药房,2016,27(23):3177-3180,4.基金项目
广东省省级重大项目（人文社科类）立项课题 （）
