37例精神分裂症患者棕榈酸帕利哌酮注射液血药浓度监测及其影响因素分析ΔOA北大核心CSTPCD
Monitoring of Plasma Concentration and Analysis of Influential Factors for Paliperidone Palmitate Injection in 37 Patients with Schizophrenia
目的：探讨精神分裂症患者棕榈酸帕利哌酮注射液血药浓度监测的影响因素。方法：选择无锡市精神卫生中心2012年9月－2015年6月使用棕榈酸帕利哌酮注射液，并进行血药浓度监测的精神分裂症患者37例，对其监测结果进行统计、分析，初步探讨其影响因素。结果：共监测棕榈酸帕利哌酮血药浓度37次，平均血药浓度（以帕利哌酮计）为（17.72±13.46）ng/ml，监测结果在目标值范围内（10～60 ng/ml）的有24次（64.86％）；男性患者平均血药浓度低…查看全部>>
OBJECTIVE:To explore the influential factors for plasma concentration of paliperidone palmitate injection for pa-tients with schizophrenia. METHODS:37 schizophrenia patients who used Paliperidone palmitate injection and took plasma concentra-tion monitoring in Wuxi Mental Health Center from Sept. 2012 to Jun. 2015 was selected,the results were statistically analyzed,and the influential factors were preliminary explored. RESULTS:Totally 37 times were conducte…查看全部>>
曲衎衎;沈珍贤;张忠东
无锡市精神卫生中心，江苏无锡 214151 南京医科大学附属无锡同仁国际康复医院，江苏无锡 214151无锡市精神卫生中心，江苏无锡 214151
医药卫生
棕榈酸帕利哌酮注射液血药浓度性别年龄日剂量联合用药精神分裂症
Paliperidone palmitate injectionPlasma concentrationGenderAgeDaily dosageDrug combinationSchizo-phrenia
《中国药房》 2016 (23)
3197-3199,3200,4
无锡市科技计划项目（No.CSZ0N1317）
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