中国药房2016，Vol.27Issue(23)：3234-3236,3237,4.DOI:10.6039/j.issn.1001-0408.2016.23.23
艾迪注射液联合TP方案治疗非小细胞肺癌的临床观察
Clinical Observation of Aidi Injection Combined with TP Regimen in the Treatment of Non-small Cell Lung Cancer
施子夏 1张劲 1张兵兵 1马铮2
作者信息
- 1. 重庆市第三人民医院胸外科，重庆 400014
- 2. 第三军医大学大坪医院胸外科，重庆 400015
- 折叠
摘要
Abstract
OBJECTIVE:To observe the clinical efficacy and safety of Aidi injection combined with TP regimen in the treat-ment of non-small cell lung cancer. METHODS:62 patients with non-small cell lung cancer were randomly divided into control group and observation group,31 cases in each group. Control group received TP regimen alone,observation group additionally re-ceived 40 ml Aidi injection,dissolved in 500 ml 0.9% Sodium chloride injection by intravenous infusion. 21 d was a treatment course,and it lasted 4 courses. The level of inflammatory cytokines before and after treatment and post-treatment quality of life, short-term efficacy,patients’satisfaction and toxicity reactions in 2 groups were compared. RESULTS:After treatment,the level of inflammatory cytokines in 2 groups were significantly lower than before,and observation group was lower than control group, the differences were statistically significant (P<0.05). The effective rate of life quality (80.64%) and short-term efficacy (83.87%)in observation group significant were higher than control group(32.25%,64.52%,respectively),the differences were statistically significant (P<0.05). Satisfaction degree (96.77%) in observation group was significantly higher than control group (77.42%);and the incidences of thrombocytopenia,leukopenia,abnormal liver function were significantly lower than control group,the differences were statistically significant (P<0.05). CONCLUSIONS:Aidi injection combined with TP regimen shows good efficacy and little toxicity in the treatment of non-small cell lung cancer,and it helps to reduce the level of inflammatory cyto-kines in patients,improving immune function and the quality of life of patients.关键词
非小细胞肺癌/TP化疗方案/艾迪注射液/疗效/炎症因子/毒副反应Key words
Non-small cell lung cancer/TP chemotherapy regimen/Aidi injection/Efficacy/Inflammatory cytokines/Toxici-ty reaction分类
医药卫生引用本文复制引用
施子夏,张劲,张兵兵,马铮..艾迪注射液联合TP方案治疗非小细胞肺癌的临床观察[J].中国药房,2016,27(23):3234-3236,3237,4.
